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Lentiviral vectors design, biological properties, milestones and current major applications, hazards. Part 2 of 2
Title
Lentiviral vectors [electronic resource] : design, biological properties, milestones and current major applications, hazards. Part 2 of 2 / Luigi Naldini.
Published
London : Henry Stewart Talks, 2014.
Physical Description
1 online resource (1 streaming video file (38 min.) : color, sound).
Local Notes
Access is available to the Yale community.
Notes
Animated audio-visual presentation with synchronized narration.
Title from title frames.
Access and use
Access restricted by licensing agreement.
Variant and related titles
Lentiviral vectors : design, biological properties, milestones and current major applications, hazards. Part 2 of 2
Format
Images / Online / Video & Film
Language
English
Added to Catalog
April 29, 2015
Series
Gene transfer and gene therapy,
System details note
Mode of access: World Wide Web.
System requirements: Browser compatibility: updated Mozilla Firefox, Google Chrome, Safari or Internet Explorer 8+. Browser settings: enable JavaScript, enable cookies from the Henry Stewart Talks site. Required Desktop Browser plugins & viewers: Updated Adobe Flash Player & Adobe Acrobat Reader. Mobile device & operating system versions: Android v2.1+, iPhone 4+ (iOS v5.x+), iPad 2+ (iOS v5.x+), BlackBerry OS v7.0+, Windows Phone v6.5.1+.
Contents
Contents: Lentiviral vectors: applications, gene transfer efficiency and transgene expression
Therapeutic potential of HSC gene therapy
Vector integration site analysis
Lentiviral-mediated HSC gene transfer
Rationale for HSC gene therapy vs. BMT
HSC gene transfer by LV: current issues
Restriction factors for lentiviral gene transfer
Ex vivo transduction by lentiviral vectors
HSC gene transfer by LV: current goals
Applications: ex vivo into hematopoietic stem cells, ex vivo into lymphocytes, In vivo gene transfer (liver and CNS)
Systemic delivery of LV: current issues
Direct LV injection into the CNS
CNS gene transfer: current issues.
Publisher's number
3821 Henry Stewart Talks
Subjects
Subjects (Medical)
Gene Transfer Techniques.
Genetic Therapy - methods.
Virus Integration - genetics.
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