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Directed evolution of novel adeno-associated viral vectors for gene therapy
Author
Title
Directed evolution of novel adeno-associated viral vectors for gene therapy [electronic resource] / David Schaffer.
Published
London : Henry Stewart Talks, 2014.
Physical Description
1 online resource (1 streaming video file (52 min.) : color, sound).
Local Notes
Access is available to the Yale community.
Notes
Animated audio-visual presentation with synchronized narration.
Title from title frames.
Access and use
Access restricted by licensing agreement.
Format
Images / Online / Video & Film
Language
English
Added to Catalog
April 29, 2015
Series
Gene transfer and gene therapy,
System details note
Mode of access: World Wide Web.
System requirements: Browser compatibility: updated Mozilla Firefox, Google Chrome, Safari or Internet Explorer 8+. Browser settings: enable JavaScript, enable cookies from the Henry Stewart Talks site. Required Desktop Browser plugins & viewers: Updated Adobe Flash Player & Adobe Acrobat Reader. Mobile device & operating system versions: Android v2.1+, iPhone 4+ (iOS v5.x+), iPad 2+ (iOS v5.x+), BlackBerry OS v7.0+, Windows Phone v6.5.1+.
Contents
Contents: Recent successes in gene therapy
Problems in the field with naturally derived vectors
Directed evolution as an approach to engineer optimal viral vector variants that meet clinical needs
Examples: development of variants to evade neutralizing antibodies and evolution for enhanced delivery in the retina.
Publisher's number
3765 Henry Stewart Talks
Subjects
Subjects (Medical)
Dependovirus - genetics.
Gene Transfer Techniques.
Genetic Therapy - methods.
Genetic Therapy - trends.
Retinal Diseases - therapy.
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