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RNAi for neurological diseases

Title
RNAi for neurological diseases [electronic resource] / Beverly L. Davidson.
Published
London : Henry Stewart Talks, 2014.
Physical Description
1 online resource (1 streaming video file (48 min.) : color, sound).
Local Notes
Access is available to the Yale community.
Notes
Animated audio-visual presentation with synchronized narration.
Title from title frames.
Access and use
Access restricted by licensing agreement.
Format
Images / Online / Video & Film
Language
English
Added to Catalog
April 29, 2015
System details note
Mode of access: World Wide Web.
System requirements: Browser compatibility: updated Mozilla Firefox, Google Chrome, Safari or Internet Explorer 8+. Browser settings: enable JavaScript, enable cookies from the Henry Stewart Talks site. Required Desktop Browser plugins & viewers: Updated Adobe Flash Player & Adobe Acrobat Reader. Mobile device & operating system versions: Android v2.1+, iPhone 4+ (iOS v5.x+), iPad 2+ (iOS v5.x+), BlackBerry OS v7.0+, Windows Phone v6.5.1+.
Contents
Contents: Repeat expansion diseases
Polyglutamine (polyQ) repeat diseases
Huntington's disease
Vectors for delivering genetic material to brain
AAVs for delivering RNAi for reducing gene expression
Artificial miRNAs
Testing miHD for efficacy
Off-target silencing
MRI-guided delivery of AAV into primates
HTT suppression
Other gain-of function diseases
Targeted infusion for broad coverage
Silencing ataxin-1
Nonallele specific silencing: experimental design
Expression and activity of miSCA1.
Publisher's number
3789 Henry Stewart Talks
Subjects (Medical)
Gene Transfer Techniques.
Genetic Therapy - methods.
MicroRNAs - therapeutic use.
Nervous System Diseases - therapy.
RNA Interference.
RNA, Small Interfering - therapeutic use.
Citation

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