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Enzymology in drug discovery part 2 of 2

Title
Enzymology in drug discovery [electronic resource] : part 2 of 2 / Robert A. Copeland.
Published
London : Henry Stewart Talks, 2013.
Physical Description
1 online resource (1 streaming video file (66 min.) : color, sound).
Local Notes
Access is available to the Yale community.
Notes
Animated audio-visual presentation with synchronized narration.
Title from title frames.
Access and use
Access restricted by licensing agreement.
Variant and related titles
Enzymology in drug discovery part, part 2 of 2
Format
Images / Online / Video & Film
Language
English
Added to Catalog
April 30, 2015
System details note
Mode of access: World Wide Web.
System requirements: Browser compatibility: updated Mozilla Firefox, Google Chrome, Safari or Internet Explorer 8+. Browser settings: enable JavaScript, enable cookies from the Henry Stewart Talks site. Required Desktop Browser plugins & viewers: Updated Adobe Flash Player & Adobe Acrobat Reader. Mobile device & operating system versions: Android v2.1+, iPhone 4+ (iOS v5.x+), iPad 2+ (iOS v5.x+), BlackBerry OS v7.0+, Windows Phone v6.5.1+.
Contents
Contents: Enzymes as targets for drug discovery
Protein-ligand binding equilibria
Enzyme reaction mechanisms
Structure and function of enzyme active sites
Measuring enzyme velocity in the laboratory
Reversible modes of enzyme inhibition
Enzyme inhibition as a mechanism of pharmacological intervention in disease
Clinical value of different inhibition modalities
Non-classical inhibition
Enzyme assays and screening criteria
Lead optimization
Summary: basic information to look for.
Publisher's number
3466 Henry Stewart Talks
Subjects (Medical)
Drug Discovery.
Citation

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