Animated audio-visual presentation with synchronized narration.

Revised version of a talk first published in 2007.

Title from title frames.

Drug metabolizing enzymes : fundamentals, study methods, recent advances and clinical significance,

Mode of access: World Wide Web.

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Contents: Mechanism of action

Reaction substrates

Isoform substrate profiles

Isoenzymes NAT1 and NAT2

Regulation of gene expression

Pharmacogenetics

Phenotype/genotype correlation

Ethnic variation

Transgenic mouse models

NAT protein structures

NAT as a biomarker in breast cancer

NAT inhibitors as diagnostic agents

NAT in mycobacteria

NAT inhibitors as an approach to potential anti-tubercular agents.

Breast > Cancer.

Drugs > Metabolism.

Bacterial diseases > drug therapy.

Enzyme inhibitors > pharmacology.

Isoenzymes > metabolism.

Mycobacterium > drug effects.

Arylamine N-Acetyltransferase - antagonists & inhibitors.

Arylamine N-Acetyltransferase - genetics.

Arylamine N-Acetyltransferase - metabolism.

Breast Neoplasms - diagnosis.

Drug Discovery - methods.

Gene Expression Regulation, Enzymologic.

Genetic Association Studies.

Mice, Transgenic.

Pharmaceutical Preparations - metabolism.