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Cancer Therapeutic Targets

Title
Cancer Therapeutic Targets [electronic resource] / edited by John L. Marshall.
ISBN
9781441907172
Publication
New York, NY : Springer New York : Imprint: Springer, 2017.
Physical Description
51 illus., 42 illus. in color. eReference : online resource.
Local Notes
Access is available to the Yale community.
Access and use
Access restricted by licensing agreement.
Summary
In the past decade, we have experienced an explosion of new information about cancer therapeutic targets. Many of the targets have been validated by the discovery and approval of new medicines which have been approved for the treatment of cancer. On the heels of these successes, innumerable new targets and new potential therapeutics are being developed by many different groups including government agencies, pharmaceutical companies, biotechnology companies, academic institutions, and individual investigators. Understanding the expanding "universe" of cancer therapies is therefore becoming impossible and no single source exists which serves as a reference for the involved parties. Further, the interested parties have vastly different areas of expertise, from focused laboratory based science, to clinical research, to corporate and regulatory oversight. The text would be updated every two years, more often depending on pace of change, interest and sales. While useful online, this reference book would likely be kept in hard copy as well.
Variant and related titles
Springer ebooks.
Other formats
Printed edition:
Format
Books / Online
Language
English
Added to Catalog
May 03, 2017
Contents
AKT
Anti-4-1BB/4-1BBL
Anti-B7-H4
Anti-CD40/Anti CD40L
Anti-Idiotype antibodies
Anti-Programmed Death 1 (PD1)
B7.1
Bacterial Vaccines
Brachyury
CCL21
CD4+ T Cells
CD8 T Cells
CEA
CTLA-4
Dendritic cells
DNA Vaccines
EGFR, Immunology
Fc Gamma R
Gangliosides
Glucocorticoid-Induced TNF Receptor (GITR)
GM-CSF and Whole Cells
gp100
HER2/neu
indoleamine 2,3-dioxygenase
Integrins, Immunology
Interferon alpha
Interleukin 2
Interleukin 7
Interleukin 12
Interleukin 15
Interleukin 21
Lymphocyte Activation Gene 3 (LAG-3)
MART-1
MUC1
NK Cells
P53, Immunology
PAP
Peptide Vaccine: Overview
Proteins (Mesothelin)
PSA
Survivin
Telomerase-related proteins
TGF Beta Receptors
TLR7 and TLR8, Resiquimod, and 852A
TLR9
Transforming Growth Factor β
Tregs
Tyrosinase: Overview
VEGF
Viral-Like Proteins
Whole-Cell Vaccines
FGF-FGFR Signaling in Cancer
MMPs
PDGF
TIE
VEGF A
VEGF Ligands
AXL
B-Raf
CKIT
DNA Repair, Overview
EGFR, Growth factors
HER3
IGF 1 and IGF 2
Jak2/Stat5a/b Pathway in Prostate Cancer
JNK Signaling in Diseases
K-Ras
MET
NEDD9
N-Ras
P38
Rac 1
Type I Insulin-Like Growth Factor Receptor
Anti-apoptotic Bcl-2
BH3-Only Mimetics
Caspase
DR4 and DR5
FLIP
MLH1
NF-κB
PARP
ROS
X-Linked IAP
APC
AR, Overview
BRCA 1 and 2
Cell Cycle Related Kinases
ER
Histone Deacetylases (HDAC)
Methylation
PR
Retinoids
Topoisomerase 1
Topoisomerase 2
VDR.
Also listed under
Marshall, John L.
SpringerLink (Online service)
Citation

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