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Understanding the Gut-Bone Signaling Axis Mechanisms and Therapeutic Implications
Title
Understanding the Gut-Bone Signaling Axis [electronic resource] : Mechanisms and Therapeutic Implications / edited by Laura R. McCabe, Narayanan Parameswaran.
ISBN
9783319666532
Publication
Cham : Springer International Publishing : Imprint: Springer, 2017.
Physical Description
XIII, 277 p. 36 illus., 29 illus. in color : online resource.
Local Notes
Access is available to the Yale community.
Access and use
Access restricted by licensing agreement.
Summary
This is the first book compiling current research on the gut-bone signaling axis and its implications in the pathophysiology of GI and bone diseases. Rather than focusing on a single mechanism, this book provides the reader with a broad view on gut-bone signaling and the most up-to-date information in this rapidly growing area. The volume is also unique in that it looks at what is known about GI diseases affecting bone and then examines the role of the microbiome and its modulation by pre and probiotics to treat bone disease, placing this topic within the context of gut-bone signaling pathways. Understanding the Gut-Bone Signaling Axis will thus provide an understanding of how various therapies could be applied to this area.
Variant and related titles
Springer ebooks.
Other formats
Printed edition:
Format
Books / Online
Language
English
Added to Catalog
December 01, 2017
Series
Advances in Experimental Medicine and Biology, 1033
Contents
Section I: Gut and Bone Physiology
1.Introduction
2.GI Research: Physiology and Gut Signaling to other organs
Section II: Gut-Bone Signaling Pathways
3. Intestinal regulation of Calcium-Vitamin D and Regulation of Bone Physiology
4. GI Regulation of Incretins and Modulation of Bone
5.Intestinal Serotonin Regulation of Bone Physiology
5. Gut Microbiome and Bone Physiology
6. Intestinal Immune System and Regulation of Bone
Section III: Gut Pathologies Affecting Bone Health
7. Stomach-Bone: Gastric Acid and Calcium Absorption
8. Inflammatory Bowel Disease: Human IBD and Mouse IBD Models
9. Antibiotic Use
10. Enteritis and Pathogens: Dysbiosis, Pediatrics and Aging
11. Enteritis and Pathogens: Chicken Models
Section IV: Modulation of the Gut Microbiota to Support Bone Health
12. Prebiotics
13
Probiotics
14. Germ Free Applications.
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