Non-viral vectors for gene therapy. Part II / edited by Leaf Huang, Mien-chie Hung, Ernst Wagner.

2nd ed.

Amsterdam ; Boston : Elsevier Academic Press, ©2005.

1 online resource (1 volume) : illustrations (some color).

Access is available to the Yale community.

Access restricted by licensing agreement.

The field of non-viral vector research has rapidly progressed since the publication of the first edition. This new edition is expanded to two separate volumes that contain in-depth discussions of different non-viral approaches, including cationic liposomes and polymers, naked DNA and various physical methods of delivery, as well as a comprehensive coverage of the molecular biological designs of the plasmid DNA for reduced toxicity, prolonged expression and tissue or disease specific genes. New developments such as the toxicity of the non-viral vectors and recent advances in nucleic acid therap.

Print version: Non-viral vectors for gene therapy. Part II. 2nd ed. Amsterdam ; Boston : Elsevier Academic Press, ©2005

Books / Online

English

May 17, 2018

Includes bibliographical references and indexes.

The mechanism of naked DNA uptake and expression / Jon A. Wolff and Vladimir Budker. Targeted delivery of therapeutic oligonucleotides to pulmonary circulation / Annette Wilson [and others] Naked DNA for liver gene transfer / Feng Liu and Pradeep Tyagi. Hydrodynamic delivery / Mohammed S. Al-Dosari, Joseph E. Knapp, and Dexi Liu. Electric pulse-mediated gene delivery to various animal tissues / Lluis M. Mir [and others] In vivo application of RNA interference: from functional genomics to therapeutics / Patrick Y. Lu, Frank Xie, and Martin C. Woodle. A novel gene expression system: non-viral gene transfer for hemophilia as model systems / Carol H. Miao. Site-specific integration with [phi]C31 integrase for prolonged expression of therapeutic genes / Daniel S. Ginsburg and Michele P. Calos. Sleeping Beauty transposon-mediated gene therapy for prolonged expression / Perry B. Hackett [and others] Cancer-specific gene therapy / Hui-Wen Lo, Chi-Ping Day, and Mien-Chie Hung. DNA vaccine / Zhengrong Cui. Airway gene therapy / Jane C. Davies and Eric W.F.W. Alton. Non-viral vector as vaccine carrier / Weihsu Claire Chen and Leaf Huang. Non-viral vectors for gene therapy: clinical trials in cardiovascular disease / Pinak B. Shah and Douglas W. Losordo.