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Viral Vectors for Treating Diseases of the Nervous System
Title
Viral Vectors for Treating Diseases of the Nervous System / edited by David S. Latchman.
ISBN
0123668565
9780123668561
9780123668561
Publication
San Diego, CA : Academic Press, 2003.
Physical Description
1 online resource (xi, 317 pages : illustrations).
Local Notes
Access is available to the Yale community.
Notes
Text in English.
Made available through: Science Direct.
Access and use
Access restricted by licensing agreement.
Summary
Gene therapy offers considerable potential for the treatment of various incurable diseases of the nervous system. This volume describes a number of different viral vectors developed for achieving high efficiency gene delivery to the brain. Vectors described include those based on adenovirus, adeno-associated virus, Herpes Simplex Virus, lentivirus, and other retroviruses. It also discusses the potential application of such viruses in treating brain tumors, Parkinson's disease, and other diseases of the nervous system. * Provides up-to-date account of gene therapy approaches for incurable neurological disorders * Describes a range of gene delivery methods based on different viruses.
Variant and related titles
Elsevier ScienceDirect All Books. OCLC KB.
Other formats
Print version: Viural vectors for treating diseases of the nervous system (print)
Format
Books / Online
Language
English
Added to Catalog
May 17, 2018
Series
International review of neurobiology ; v. 55
Bibliography
Includes bibliographical references and index.
Contents
Section I. Virus vectors for use in the central nervous system. Nonneurotropic adenovirus: a vector for gene transfer to the brain and gene therapy of neurological disorders / Pedro R. Lowenstein [and others]. Adeno-associated viral vectors / E. Lehtonen and L. Tenenbaum. Problems in the use of herpes simplex virus as a vector / Lawrence T. Feldman. Lentiviral vectors / Johan Jakobsson [and others]. Retroviral vectors for gene delivery to neural precursor cells / Ryoichiro Kageyama, Hiromi Hirata, and Jun Hatakeyama
Section II. Gene therapy with virus vectors for specific diseases of the nervous system. The principles of molecular therapies for glioblastoma / George Karpati and Josephine Nalbantoglu. Oncolytic herpes simplex virus for tumor therapy / Jennifer C.C. Hu and Robert S. Coffin. Recombinant retrovirus vectors for treatment of malignant brain tumors / Nikolai G. Rainov and Christof M. Kramm. Adeno-associated viral vectors for Parkinson's Disease / Shin-ichi Muramatsu [and others]. Herpes simplex virus vectors for Parkinson's Disease / David S. Latchman. Gene therapy for stroke / K. Abe and W.R. Zhang. Gene therapy for mucopolysaccharidosis / Assumpcio Bosch and Jean Michel Heard.
Subjects
Subjects (Medical)
Genetic Vectors.
Genetic Therapy.
Nervous System Diseases - therapy.
Adenoviridae.
Retroviridae.
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