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Imaging Mass Spectrometry Methods and Protocols
Title
Imaging Mass Spectrometry [electronic resource] : Methods and Protocols / edited by Laura M. Cole.
ISBN
9781493970513
Publication
New York, NY : Springer New York : Imprint: Humana Press, 2017.
Physical Description
1 online resource (X, 204 p.) 84 illus., 68 illus. in color.
Local Notes
Access is available to the Yale community.
Access and use
Access restricted by licensing agreement.
Summary
This volume addresses the various techniques and novel applications of mass spectrometry imaging (MSI) and its role as a discovery tool in the field of proteomics, lipidomics, and metabolomics. The chapters in this book demonstrate how MSI can be applied to many areas of research such as clinical pathology, translational medicine, toxicology, biomarkers and response studies, and potential incorporation of MSI into forensic workflows. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Innovative and comprehensive, Imaging Mass Spectrometry: Methods and Protocols is a valuable resource for research scientists and clinicians who are interested in further studies of MSI technologies.
Variant and related titles
Springer protocols (Series)
Other formats
Printed edition:
Format
Books / Online
Language
English
Added to Catalog
August 31, 2018
Series
Methods in Molecular Biology, 1618
Contents
‘A Future Amalgamation between the Scientist and the Clinician?’
Fresh Frozen Versus Formalin Fixed Paraffin Embedded for Mass Spectrometry Imaging
Imaging MS of Rodent Ocular Tissues and the Optic Nerve
MALDI-MSI of Lipids in Human Skin
MALDI-MSI Analysis of Cytological Smears: The Study of Thyroid Cancer
Droplet-Based Liquid Extraction for Spatially-Resolved Microproteomics Analysis of Tissue Sections
DESI Mass Spectrometry Imaging (MSI)
Peptide Imaging: Maximizing Peptide Yield, Optimization of the ‘Peptide Mass Fingerprint’
MALDI-MS Imaging in the Study of Glomerulonephritis
Hierarchical Cluster Analysis to Aid Diagnostic Image Data Visualization of MS and Other Medical Imaging Modalities
Laser Ablation Inductively Coupled Plasma Mass Spectrometry Imaging of Plant Metabolites
Mass Spectrometry Imaging of Drugs of Abuse in Hair
MALDI Mass Spectrometry Profiling and Imaging Applied to the Analysis of Latent Fingermarks
ToF-SIMS Parallel Imaging MS/MS of Lipid Species in Thin Tissue Sections
Rodent Whole-Body Sectioning and MALDI Mass Spectrometry Imaging
The Future in Disease Models for Mass Spectrometry Imaging, Ethical Issues and the Way Forward. .
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