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Characterization of Nanoparticles Intended for Drug Delivery
Title
Characterization of Nanoparticles Intended for Drug Delivery [electronic resource] / edited by Scott E. McNeil.
ISBN
9781493973521
Edition
2nd ed. 2018.
Publication
New York, NY : Springer New York : Imprint: Humana Press, 2018.
Physical Description
1 online resource (XII, 256 p.) 72 illus., 40 illus. in color.
Local Notes
Access is available to the Yale community.
Access and use
Access restricted by licensing agreement.
Summary
This second edition volume expands on the first edition by providing up-to-date protocols to characterize nanomaterials used as drug delivery agents. The chapters in this book are divided into 5 parts and cover topics such as: advances and obstacles in nanomedicine research; methods to test sterility and endotoxin, physicochemical features, immunological effects, drug release, and in vivo efficacy. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Characterization of Nanoparticles Intended for Drug Delivery, Second Edition is a valuable tool for researchers and pharmaceutical and biotechnology developers who are evaluating the clinical potential of nanomedicines in preclinical studies.>.
Variant and related titles
Springer protocols (Series)
Other formats
Printed edition:
Format
Books / Online
Language
English
Added to Catalog
August 31, 2018
Series
Methods in Molecular Biology, 1682
Contents
Evaluating Nanomedicines: Obstacles and Advancements
Detection of Bacterial Contamination in Nanoparticle Formulations by Agar Plate Test
Considerations and Some Practical Solutions to Overcome Nanoparticle Interference with LAL Assays and to Avoid Endotoxin Contamination in Nanoformulations
Elemental Analysis in Biological Matrices Using ICP-MS
PEG Quantitation Using Reversed Phase High Performance Liquid Chromatography and Charged Aerosol Detection
Quantitation of Surface Coating on Nanoparticles Using Thermogravimetric Analysis
Immunoelectron Microscopy for Visualization of Nanoparticles
Imaging of Liposomes by Transmission Electron Microscopy
Updated Method for In Vitro Analysis of Nanoparticle Hemolytic Properties
In Vitro Assessment of Nanoparticle Effects on Blood Coagulation
In Vitro Analysis of Nanoparticle Effects on the Zymosan Uptake by Phagocytic Cells
Assessing NLRP3 Inflammasome Activation by Nanoparticles
Analysis of Complement Activation by Nanoparticles
Methods for Analysis of Nanoparticle Immunosuppressive Properties In Vitro and In Vivo
Analysis of Pro-Inflammatory Cytokine and Type II Interferon Induction by Nanoparticles
Analysis of Nanoparticle Adjuvant Properties In Vivo
In Vitro and In Vivo Methods for Analysis of Nanoparticle Potential to Induce Delayed Type Hypersensitivity Reactions
Autophagy Monitoring Assay II: Imaging Autophagy Induction in LLC-PK1 Cells Using GFP-LC3 Protein Fusion Construct
Improved Ultrafiltration Method to Measure Drug Release from Nanomedicines Utilizing a Stable Isotope Tracer
Designing an In Vivo Efficacy Study of Nanomedicines for Preclinical Tumor Growth Inhibition.
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