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Breast Cancer Metastasis and Drug Resistance Progress and Prospects
Title
Breast Cancer Metastasis and Drug Resistance [electronic resource] : Progress and Prospects / edited by Aamir Ahmad.
ISBN
9781461456476
Publication
New York, NY : Springer New York : Imprint: Springer, 2013.
Physical Description
1 online resource (XII, 416 p.)
Local Notes
Access is available to the Yale community.
Access and use
Access restricted by licensing agreement.
Summary
This comprehensive book on breast cancer brings together some of the leading experts in an attempt to better understand breast cancer disease, the factors that make it lethal and current research progress, integrating both basic research with clinical implications. This volume covers the following core issues: i) heterogeneity in breast cancer – statistics, epidemiology, breast cancer subtypes, racial disparity and the associated challenges, ii) available and upcoming model systems in breast cancer research, iii) breast cancer metastasis to bones and brain, iv) drug resistance mechanisms in breast cancer against targeted therapies and v) recent developments in breast cancer research – state of current research directions / technologies / approaches. With its comprehensive coverage of topics related to breast cancer, this volume is expected to have a very wide appeal. It serves as an excellent source of reference for students/beginning researchers just setting foot in the field and interested in getting to know all the aspects of this disease. The book should also appeal to advanced and senior researchers by bringing everyone up-to-date with the most current knowledge on various breast cancer topics of utmost relevance.
Variant and related titles
Springer ENIN.
Other formats
Printed edition:
Printed edition:
Printed edition:
Format
Books / Online
Language
English
Added to Catalog
April 11, 2019
Contents
Preface
Breast Cancer Statistics
Epidemiology of Breast Cancer in Women
The Complexities of Racial Disparity in Breast Cancer
Major signaling pathways involved in Breast Cancer
Breast Cancer Heterogeneity in Primary and Metastatic Disease
Understanding Triple-negative Breast Cancer
The biology of the deadly love connection between obesity, diabetes and breast cancer
Progression of Early Breast Cancer to an Invasive Phenotype
Pre-clinical modeling of breast cancer – which model to choose?
Modeling breast cancer progression in 4-D
Bone Metastasis of Breast Cancer
Cellular and Molecular Mechanisms Involved in Breaching of The Blood-Brian Barrier By Circulating Breast Cancer Cells
Resistance to Anthracyclines and Taxanes in Breast cancer
Understanding of Tamoxifen Resistance of Breast Cancer based on Integrative Bioinformatics Approaches
Current understanding of drug resistance mechanisms and therapeutic targets in HER2 overexpressing breast cancers
Platinum and ruthenium complexes for the therapy of breast cancer diseases.-Development of Notch Pathway Inhibitors for Cancer Therapy
Systems Biology Approaches in Breast Cancer Studies
Epigenetic Factors in Breast Cancer Progression
Breast Cancer Stem Cells and miRNAs
Breast Cancer Stem Cells: responsible for therapeutic resistance and relapse?
MicroRNAs in Breast Cancer Research: Progress and Promise
Index.
Subjects
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