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An introduction to systems biology : design principles of biological circuits

Title
An introduction to systems biology : design principles of biological circuits / Uri Alon.
ISBN
9781439837177
1439837171
9781138490116
1138490113
9780429283321
9781000008166
9781000001327
9781000014686
Edition
Second edition.
Publication
Boca Raton, Fla. : CRC Press, [2020]
Physical Description
xviii, 324 pages : illustrations (some color) ; 26 cm
Other formats
ebook version :
Format
Books
Language
English
Added to Catalog
December 12, 2019
Bibliography
Includes bibliographical references and index.
Contents
Part 1. Network motifs
Transcription networks : basic concepts
Autoregulation : a network motif
The feed forward loop network motif
Temporal programs and the global structure of transcription networks
Positive feedback, bistability and memory
How to build a biological oscillator
Part 2. Robustness
Kinetic proofreading and conformational proofreading
Robust signalling by bifunctional componets
Robustness in bacterial chemotaxis
Fold-change detection
Dynamical compensation and mutal resistance in tissues
Robust spatial patterning in development
Part 3. Optimality
Optimal gene circuit design
Multi-objective optimality in biology
Modularity.
Citation

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