Books+ Search Results

Pharmacological Mechanisms in Alzheimer's Therapeutics

Title
Pharmacological Mechanisms in Alzheimer's Therapeutics [electronic resource] / edited by A. Claudio Cuello.
ISBN
9780387715223
Edition
1st ed. 2007.
Publication
New York, NY : Springer New York : Imprint: Springer, 2007.
Physical Description
1 online resource (XX, 324 p.) 35 illus.
Local Notes
Access is available to the Yale community.
Access and use
Access restricted by licensing agreement.
Summary
Alzheimer’s is the most common dementia in the elderly. The need for effective therapy of dementia is greater than ever, but there is not, as yet, a drug therapy which can stop or reverse the clinical consequences. There is, however, a great deal of anticipation on the imminent development of effective, disease-modifying therapies. The remarkable progress made by the scientific community in unraveling molecular and cellular aspects of the Alzheimer’s pathology has allowed the identification of a number of promising targets for drug development. Investigation of these targets and the evolution of ongoing strategies to develop efficacious therapies for this devastating neurodegenerative condition is the central theme of Pharmacological Mechanisms in Alzheimer’s Therapeutics. The current and future therapies based on this new knowledge of the Alzheimer’s pathology are dealt with by contributors who have been most influential in bringing this new knowledge and in the development of experimental and presently applied therapies. The book should be of interest to medical professionals and basic scientists alike since it provides ideas about current trends in Alzheimer’s therapeutics to the general public.
Variant and related titles
Springer ENIN.
Other formats
Printed edition:
Printed edition:
Printed edition:
Format
Books / Online
Language
English
Added to Catalog
February 07, 2020
Contents
Overview of the Alzheimer's Disease Pathology and Potential Therapeutic Targets
Trial Designs and Outcomes to Monitor Novel Therapeutics in Alzheimer's Disease
The Pharmacological Treatment of Alzheimer's Disease with Cholinesterase Inhibitors and Memantine
M1 Muscarinic Agonists: A Comprehensive Therapy Against Major Hallmarks of Alzheimer's Disease
Cholinergic Neurodegeneration in Alzheimer's Disease: Basis for Nerve Growth Factor Therapy
The Rationale for Glutamatergic Therapy in Alzheimer's Disease
Secretases as Pharmacological Targets in Alzheimer's Disease
?-Secretase as a Target for Alzheimer's Disease
The Rationale for an Immunological Approach to Alzheimer's Therapeutics
Neuroinflammation, Alzheimer Disease, and Other Aging Disorders
Nonsteroidal Anti-inflammatory Drugs (NSAIDs) and Derived A?42-Lowering Molecules for Treatment and Prevention of Alzheimer's Disease (AD)
The Potential Application of Antioxidant Agents in Alzheimer Disease Therapeutics
Apolipoprotein E: A Potent Gene-Based Therapeutic Target for the Treatment of Sporadic Alzheimer's Disease
Tau Pathology as a Target in Alzheimer's Therapeutics
Design of Inhibitors of Amyloid-? Misfolding and Aggregation for Alzheimer's Therapy
Potential Applications of Glycosaminoglycan-Related Compounds in Alzheimer's Disease
Multifunctional Neuroprotective Drugs for the Treatment of Alzheimer's Disease
Interpreting Clinical Studies of Putative Therapeutics for Alzheimer's Disease: The Case of Statins and NSAIDs.
Subjects
Also listed under
Cuello, A. Claudio.
SpringerLink (Online service)
Citation

Available from:

Online
Loading holdings.
Unable to load. Retry?
Loading holdings...
Unable to load. Retry?