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Continuous biopharmaceutical processes : chromatography, bioconjugation, and protein stability
Title
Continuous biopharmaceutical processes : chromatography, bioconjugation, and protein stability / David Pfister, Lucrèce Nicoud, Massimo Morbidelli.
ISBN
9781108332897 (ebook)
9781108420228 (hardback)
Publication
Cambridge : Cambridge University Press, 2018.
Physical Description
1 online resource (xix, 327 pages) : digital, PDF file(s).
Local Notes
Access is available to the Yale community.
Notes
Title from publisher's bibliographic system (viewed on 24 Sep 2018).
Access and use
Access restricted by licensing agreement.
Summary
This innovative reference provides a coherent and critical view on the potential benefits of a transition from batch to continuous processes in the biopharmaceutical industry, with the main focus on chromatography. It also covers the key topics of protein stability and protein conjugation, addressing the chemical reaction and purification aspects together with their integration. This book offers a fine balance between theoretical modelling and illustrative case studies, between fundamental concepts and applied examples from the academic and industrial literature. Scientists interested in the design of biopharmaceutical processes will find useful practical methodologies, in particular for single-column and multi-column chromatographic processes.
Variant and related titles
Cambridge University Press eBook Backlist 2018-2019.
Other formats
Print version:
Format
Books / Online
Language
English
Added to Catalog
June 05, 2020
Series
Cambridge series in chemical engineering
Contents
Introduction to biopharmaceutical processes
Fundamentals of protein chromatography
Counter-current separation processes
Counter-current chromatography for the capture step
Counter-current chromatography for the polishing steps
Protein conjugation
Protein aggregation in biopharmaceutical processes.
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