1849738912

9781849738910

9781782622215

1782622217

6.2 The Role of ICP-MS in Selenoproteins Speciation

English.

Food and Nutritional Components in Focus,

Cover; Selenium Chemistry, Analysis, Function and Effects ; Preface; Section I Chemistry and Biochemistry ; Chapter 1

The Chemistry of Selenium; 1.1 Chemical Properties of Selenium; 1.2 Organoselenium Compounds; 1.3 Selenium in Soil and Foods; Summary Points; Keys Facts of Seleno proteins ; Definitions and Explanations of Key Terms; List of Abbreviations; References; Chapter 2

Biochemistry and Molecular Biology of Selenoproteins; 2.1 Selenoproteins in Mammals; 2.1.1 Thioredoxin Reductases; 2.1.2 Glutathione Peroxidases; 2.1.3 Selenoprotein P; 2.1.4 Selenoprotein N

2.1.5 Iodothyronine Deiodinases2.1.6 Selenoprotein R is a Methionine-Sulfoxide-Reductase; 2.1.7 Selenoproteins Involved in Protein Biosynthesis, Folding or Degradation; 2.2 Selenoprotein Biosynthesis; 2.2.1 Biosynthesis of Selenocysteine; 2.2.1.1 Selenocysteine Biosynthesis Occurs on its tRNA; 2.2.1.2 Seryl-tRNA Synthetase (SerRS); 2.2.1.3 O-Phosphoseryl-tRNASec Kinase (PSTK); 2.2.1.4 Selenocysteine Synthetase (SepSecS); 2.2.1.5 Selenophosphate Synthetases; 2.2.2 Translation of Selenoproteins; 2.2.2.1 The Hierarchy of Selenoproteins; 2.2.2.2 SECIS-Binding Protein 2 (SECISBP2)

2.2.2.3 Sec-Specific Eukaryotic Elongation Factor (EFSec)2.2.2.4 SECp43; 2.2.2.5 Selenocysteine Insertion Sequence (SECIS) Element; 2.2.2.6 Selenocysteine Redefinition Element (SRE); 2.2.2.7 tRNA[Ser]Sec; Summary Points; Key Facts: Recoding of UGA; Key Facts: Mutations in SECISBP2; Definitions; List of Abbreviations; References; Chapter 3 Synthesis of Organoselenium Derivatives of Biological Relevance ; 3.1 Introduction; 3.2 Isoselenocyanates and Related Selenoxo Compounds ; 3.3 Selenosugars; 3.4 Ebselen and Derivatives; 3.5 Miscellaneous; Summary Points; Key Facts

Definitions of Words and TermsList of Abbreviations; Acknowledgements; References; Chapter 4

Chemistry and Activity of Selenium Dioxide and Selenite Ions; 4.1 Introduction; 4.2 Oxidation State and Speciation in Aqueous Solution; 4.3 SeO32− as a Nutritional Supplement; 4.4 Pro-Oxidant Behavior; 4.4.1 Oxidative Activity of SeO2; 4.4.2 ROS Formation and SeO32−; 4.4.3 Chemopreventive and Chemotherapeutic Activity of SeO32−; 4.5 Interactions with Metal Ions; 4.5.1 Role of SeO32− in Mediating Metal Toxicity; 4.5.2 SeO2 and SeO32− as Antioxidants; 4.6 Conclusion; Summary Points; Key Facts

Definitions and Explanation of Key TermsList of Abbreviations; References; Chapter 5

Chemistry and Biochemistry: Selenium Species in Fish; 5.1 Background; 5.2 Selenoproteins; 5.3 Low Molecular Mass Organoselenium Compounds; 5.4 Conclusions; Summary Points; Key Facts; Key Facts of Selenoprotein L (SelL); Key Facts of Fish 15 kDa Selenoprotein-like Protein (Fep15); Definitions of Words and Terms; List of Abbreviations; References; Section II Analysis ; Chapter 6

Current Analytical Strategies and Techniques Related to Selenoproteins in Foods ; 6.1 Introduction; 6.1.1 Selenoproteins in Food

Selenium in human nutrition > Physiological effect.

Selenium.

Trace Elements.

Dietary Supplements.

Physiology.

Food, Fortified.

Pharmacology.

Chalcogens.

Minerals.

Micronutrients.

Biological Science Disciplines.

Foods, Specialized.

Food.

Inorganic Chemicals.

Natural Science Disciplines.

Elements.

Food and Beverages

Growth Substances.

Physiological Effects of Drugs

Disciplines and Occupations

Technology, Industry, Agriculture

Chemicals and Drugs

Pharmacologic Actions

Chemical Actions and Uses