List of Contents
1. General
The Macrophage as a Validated Pharmaceutical Target
Transcription Factors that Regulate Macrophage Development and Function
Exploitation of Macrophage Clearance Functions In Vivo
Reaching the Macrophages: Routes of Delivery
Antigen Presenting Cells and Vaccine Design
Macrophage-Specific Gene Targeting In Vivo
2. Macrophage Targets in Inflammation
Integrins of Macrophages and Macrophage-Like Cells
Macrophage Targets in Inflammation: Purinergic Receptors
Macrophage Lipid Uptake and Foam Cell Formation
Dietary Fatty Acids and Macrophages
Macrophages as Therapeutic Targets in Lysosomal Storage Disorders
Nuclear Receptors as Regulators of Macrophage Homeostasis and Function
Relationships between Reactive Oxygen Species and Reactive Nitrogen Oxide Species Produced by Macrophages
Proteases
Targeting the Chemokine System
Antimicrobial Peptides
Macrophage Phospholipid Products
3. Modulation of Specialised Macrophage Activities
Dendritic Cells Versus Macrophages as Antigen-Presenting Cells: Common and Unique Features
The Osteoclast
Macrophages in the Central and Peripheral Nervous System
Innate Recognition of Viruses by Macrophage and Related Receptors: Potential Ligand for Antiviral Agents
Macrophage Immunity and Mycobacterium Tuberculosis
Detection and Control of Fungi by Macrophages: The Role of Carbohydrates and Antifungal Agents.