Frontmatter
Contents
Acknowledgments
Introduction
Part I: Why Do We Need Toxicology?
1. Cancer Clusters: Truth Can Be Obscure
2. Death from Arsenic and Venoms: Truth Can Be Obvious
3. Paracelsus: The Alchemist at Work
4. Mining and the Beginnings of Occupational Medicine
5. The Chemical Age
6. The Bioassay Boom
Part II: How Do We Study Toxicology, and What Have We Learned?
7. Lead: A Heavy Metal Weighing Down the Brain
8. Rachel Carson: Silent Spring Is Now Noisy Summer
9. The Study of Cancer
10. How Are Carcinogens Made?
11. Some Carcinogens Directly Affect Genes
12. Cancer Caused by Irritation
13. Cigarette Smoking: Black, Tarry Lungs
14. What Causes Cancer?
Part III: How Do We Use Toxicology?
15. Protecting Workers from Chemical Diseases
16. The Importance of Having a Good Name
17. Can We Accurately Regulate Chemicals?
18. The Dose Makes the Poison
19. Are We Ready to Clean Up the Mess?
20. Legal Battles
21. The Toxicology of War
Part IV: The Unfinished Business of Toxicology
22. Opiates and Politics
23. The Toxicology of Climate Change
24. Animal Models for Human Disease
25. Are Animal Cancer Bioassays Reliable?
26. Hormone Mimics and Disrupters
27. Building Better Tools for Testing
28. An Ounce of Prevention Is Worth a Pound of Cure
Notes
Index