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Application of Omic Techniques to Identify New Biomarkers and Drug Targets for COVID-19

Title
Application of Omic Techniques to Identify New Biomarkers and Drug Targets for COVID-19 [electronic resource] / edited by Paul C. Guest.
ISBN
9783031280122
Edition
1st ed. 2023.
Publication
Cham : Springer International Publishing : Imprint: Springer, 2023.
Physical Description
1 online resource (XI, 513 p.) 87 illus., 74 illus. in color.
Local Notes
Access is available to the Yale community.
Access and use
Access restricted by licensing agreement.
Summary
The COVID-19 pandemic caused by the SARS-CoV-2 virus has affected nearly every country and territory in the world. Although worldwide vaccination efforts have reduced the risk of serious disease outcomes, disparities in distribution have led to multiple waves of SARS-CoV-2 outbreaks and the emergence of variants of concern, some of which have enhanced infectivity and ability to evade existing vaccines. Hence there is an increasing interest in understanding the evolution of viruses like SARS-CoV-2, as well as improving our capacity to effectively current and manage future pandemics. This new volume reviews the most effective omic techniques for increasing our understanding of COVID-19, to improve diagnostics, prognostics, and genomic surveillance, and to facilitate development of effective treatments and vaccines. Chapters are written by an international team of experts and explore methods in the areas of genomics, transcriptomics, proteomics, and metabolomics. Techniques used to assess physiological function at the molecular level and artificial intelligence approaches used for more effective validation and translation of biomarker candidates into clinical use are also discussed. This book is an excellent resource for researchers studying biomarkers, virology, metabolic diseases, and infectious diseases, as well as clinical scientists, physicians, drug company scientists, and healthcare workers.
Variant and related titles
Springer ENIN.
Other formats
Printed edition:
Printed edition:
Printed edition:
Format
Books / Online
Language
English
Added to Catalog
July 07, 2023
Series
Proteomics, Metabolomics, Interactomics and Systems Biology, 1412
Proteomics, Metabolomics, Interactomics and Systems Biology, 1412
Contents
Chapter 1. The COVID-19 Pandemic: SARS-CoV-2 Structure, Infection, Transmission, Symptomology and Variants of Concern
Chapter 2. Long-term Vaccination and Treatment Strategies for COVID-19 Disease and Future Coronavirus Pandemics
Chapter 3. Consequences of the Lockdown - Domestic Violence during the COVID-19 Pandemic
Chapter 4. Psychological distress impact of Coronavirus disease (COVID-19) outbreak on three continents: A systematic review and meta-analysis
Chapter 5. A Molecular Biomarker-based Triage Approach for Targeted Treatment of Post-COVID-19 Syndrome Patients with Persistent Neurological or Neuropsychiatric Symptoms
Chapter 6. Genetic Associations with Coronavirus Susceptibility and Disease Severity
Chapter 7. COVID Diagnostics: from Molecules to Omics
Chapter 8. Assessing Biomarkers in Viral Infection
Chapter 9. Proteomic Investigation of COVID-19 Severity During the Tsunamis Second Wave in Mumbai
Chapter 10. NMR-Metabolomics in COVID-19 Research
Chapter 11. Potential Biomarkers of Mitochondrial Dysfunction Associated with COVID-19 Infection
Chapter 12. Red Cell Distribution Width as a Prognostic Indicator for Mortality and ICU Admission in Patients with COVID-19
Chapter 13. Predicting the COVID-19 Patients Status using Chest CT Scan Findings: A Risk Assessment Model Based on Decision Tree Analysis
Chapter 14. Inferring Recombination Events in SARS-CoV-2 Variants In Silico
Chapter 15. Amplicon-based Nanopore Sequencing of Patients Infected by the SARS-CoV-2 Omicron (B.1.1.529) Variant in India
Chapter 16. Perspectives on Rapid Antigen Tests for Downstream Validation and Development of Theranostics
Chapter 17. Machine Learning and COVID-19: Lessons from SARS-CoV-2
Chapter 18. The Relationship between Psoriasis, COVID-19 Infection and Vaccination during Treatment of Patients
Chapter 19. Immunogenicity of Inactivated SARS-CoV-2 Vaccine (BBIBP-CorV; Sinopharm) and Short-term Clinical Outcomes in Vaccinated Solid Organ Transplant Recipients: A Prospective Cohort Study
Chapter 20. Spices and Biomarkers of COVID-19: A Mechanistic and Therapeutic Perspective
Chapter 21. Antiviral Mechanisms of Curcumin and its Derivatives in Prevention and Treatment of COVID-19: A review
Chapter 22. Evaluation of Curcumin-Piperine Supplementation in COVID-19 Patients Admitted to the Intensive Care: A Double-Blind, Randomized Controlled Trial
Chapter 23. Chronobiological Efficacy of Combined Therapy of Pelargonium Sidoides and Melatonin in Acute and Persistent Cases of COVID-19: A Hypothetical Approach
Chapter 24. The Potential Effect of Royal Jelly on Biomarkers Related to COVID-19 Infection and Severe Progression
Chapter 25. Statins: Beneficial Effects in Treatment of COVID-19
Chapter 26. Multiplex Immunoassay Approaches Using Luminex® xMAP® Technology for the Study of COVID-19 Disease
Chapter 27. Rapid Detection of SARS-CoV-2 Variants of Concern by Genomic Surveillance Techniques.
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Guest, Paul C. editor.
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