Section I: General Principles
Chapter 1: Drug Invention and the Pharmaceutical Industry
Chapter 2: Pharmacokinetics: The Dynamics of Drug Absorption, Distribution, Metabolism, and Elimination
Chapter 3: Pharmacodynamics: Molecular Mechanisms of Drug Action
Chapter 4: Drug Toxicity and Poisoning
Chapter 5: Membrane Transporters and Drug Response
Chapter 6: Drug Metabolism
Chapter 7: Pharmacogenetics
Section II: Neuropharmacology
Chapter 8: Neurotransmission: The Autonomic and Somatic Motor Nervous Systems
Chapter 9: Muscarinic Receptor Agonists and Antagonists
Chapter 10: Anticholinesterase Agents
Chapter 11: Agents Acting at the Neuromuscular Junction and Autonomic Ganglia
Chapter 12: Adrenergic Agonists and Antagonists
Chapter 13: 5-Hydroxytryptamine (Serotonin) and Dopamine
Chapter 14: Neurotransmission and the Central Nervous System
Chapter 15: Drug Therapy of Depression and Anxiety Disorders
Chapter 16: Pharmacotherapy of Psychosis and Mania
Chapter 17: Hypnotics and Sedatives
Chapter 18: Opioids, Analgesia, and Pain Management
Chapter 19: General Anesthetics and Therapeutic Gases
Chapter 20: Local Anesthetics
Chapter 21: Pharmacotherapy of the Epilepsies
Chapter 22: Treatment of Central Nervous System Degenerative Disorders
Chapter 23: Ethanol and Methanol
Chapter 24: Drug Addiction
Section III: Modulation of Cardiovascular Function
Chapter 25: Regulation of Renal Function and Vascular Volume
Chapter 26: Renin and Angiotensin
Chapter 27: Treatment of Myocardial Ischemia and Hypertension
Chapter 28: Pharmacotherapy of Congestive Heart Failure
Chapter 29: Anti-Arrhythmic Drugs
Chapter 30: Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs
Chapter 31: Drug Therapy for Hypercholesterolemia and Dyslipidemia
Section IV: Inflammation, Immunomodulation, and Hematopoiesis
Chapter 32: Histamine, Bradykinin, and Their Antagonists
Chapter 33: Lipid-Derived Autacoids: Eicosanoids and Platelet-Activating Factor
Chapter 34: Pharmacotherapy of Inflammation, Fever, Pain, and Gout
Chapter 35: Immunosuppressants, Tolerogens, and Immunostimulants
Chapter 36: Pulmonary Pharmacology
Chapter 37: Hematopoietic Agents: Growth Factors, Minerals, and Vitamins
Section V: Hormones and Hormone Antagonists
Chapter 38: Introduction to Endocrinology: The Hypothalamic-Pituitary Axis
Chapter 39: Thyroid and Anti-Thyroid Drugs
Chapter 40: Estrogens and Progestins
Chapter 41: Androgens
Chapter 42: Pharmacology of the Adrenal Cortex
Chapter 43: Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus and Hypoglycemia
Chapter 44: Agents Affecting Mineral Ion Homeostasis and Bone Turnover
Section VI: Drugs Affecting Gastrointestinal Function
Chapter 45: Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease
Chapter 46: Gastrointestinal Motility and Water Flux; Emesis; Biliary and Pancreatic Disease
Chapter 47: Pharmacotherapy of Inflammatory Bowel Disease
Section VII: Chemotherapy of Microbial Diseases.
Chapter 48: General Principles of Antimicrobial Therapy
Chapter 49: Chemotherapy of Malaria
Chapter 50: Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections
Chapter 51: Chemotherapy of Helminth Infections
Chapter 52: Sulfonamides, Trimethoprim-Sulfamethoxazole, Quinolones, and Agents for Urinary Tract Infections
Chapter 53: Penicillins, Cephalosporins, and Other β-Lactam Antibiotics
Chapter 54: Aminoglycosides
Chapter 55: Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agents
Chapter 56: Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy
Chapter 57: Antifungal Agents
Chapter 58: Antiviral Agents (Nonretroviral)
Chapter 59: Antiretroviral Agents and Treatment of HIV Infection
Section VIII: Chemotherapy of Neoplastic Diseases
Chapter 60: General Principles of Cancer Chemotherapy
Chapter 61: Cytotoxic Agents
Chapter 62: Targeted Therapies: Tyrosine Kinase Inhibitors, Monoclonal Antibodies, and Cytokines
Chapter 63: Natural Products in Cancer Chemotherapy: Hormones and Related Agents
Section IX: Special Systems Pharmacology
Chapter 64: Ocular Pharmacology
Chapter 65: Dermatological Pharmacology
Chapter 66: Contraception and Pharmacotherapy of Obstetrical and Gynecological Disorders
Chapter 67: Environmental Toxicology: Carcinogens and Heavy Metals
Appendix I: Principles of Prescription Order Writing and Patient Compliance.