Chapter 1: Why study Drug Resistant Epilepsy?
Chapter 2: Pharmacoresistance in Epilepsy
Chapter 3: Experimental models for the study of drug-resistant epilepsy
Chapter 4: On Complexity and Emergence: Linking the Hypotheses of Pharmacoresistance in Epilepsy
Chapter 5: Role of High-Frequency Oscillation Networks in Managing Pharmacoresistant Epilepsy
Chapter 6: Transporter hypothesis in pharmacoresistant epilepsies. Is it at the central or peripheral level?
Chapter 7: Changes in Targets as an Explanation for Drug Resistance in Epilepsy
Chapter 8: Cellular and molecular mechanisms of neuroinflammation in drug-resistant epilepsy
Chapter 9: Contribution of the antiepileptic drug administration regime to avoid the development and/or establishment of pharmacoresistant epilepsy
Chapter 10: Pharmacogenetics in Epilepsy and Refractory Epilepsy
Chapter 11: Seizures Induce Hypoxia or Hypoxia Induces Seizures. A Perverse Relationship that Increases the Risk of SUDEP
Chapter 12: Neonatal excitotoxicity triggers degenerative processes related to seizure susceptibility and pharmacoresistance
Chapter 13: Cerebrovascular remodeling and the role of vascular endothelial growth factor in the epileptic brain and pharmacoresistance
Chapter 14: The Role of JNK3 in Epilepsy and Neurodegeneration
Chapter 15: Application of proteomics in the study of molecular markers in epilepsy
Chapter 16: GABAergic neurotransmission abnormalities in pharmacoresistant epilepsy: experimental and human studies
Chapter 17: Genes involved in pharmacoresistant epilepsy
Chapter 18: Drug-resistant Epilepsy and the Influence of Age, Gender and Comorbid Disorders
Chapter 19: Indications for Intracerebral Recording in Candidates for Epilepsy Surgery
Chapter 20: On the Development of New Drugs for the Treatment of Drug Resistant Epilepsy: An Update on Different Approaches to Different Hypotheses
Chapter 21: Physical exercise as a strategy to reduce seizure susceptibility
Chapter 22: Ketogenic Diet and Drug-resistant Epilepsy
Chapter 23: Modulating P-glycoprotein Regulation as a Therapeutic Strategy for Pharmacoresistant Epilepsy
Chapter 24: Vagus Nerve Stimulation for Intractable Seizures
Chapter 25: Non Invasive Brain Stimulation as a potential Therapeutic Procedure in drug-resistant epilepsy
Chapter 26: Effects of transcranial focal electrical stimulation via concentric ring electrodes on seizure activity.