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Microfluidics and Multi Organs on Chip
Title
Microfluidics and Multi Organs on Chip [electronic resource] / edited by P. V. Mohanan.
ISBN
9789811913792
Edition
1st ed. 2022.
Publication
Singapore : Springer Nature Singapore : Imprint: Springer, 2022.
Physical Description
1 online resource (IX, 717 p.) 1 illus.
Local Notes
Access is available to the Yale community.
Access and use
Access restricted by licensing agreement.
Summary
This book highlights the application of microfluidics in cell biology research, chemical biology, and drug discovery. It covers the recent breakthroughs and prospects of organ-on-a-chip, human-on-a-chip, multi-organ-on-a-chip for personalized medicine. The book presents the preclinical studies of organs-on-a-chip, concepts of multiple vascularized organ-on-chips, application of organ-on-a-chip in blood-brain barrier model, culture and co-culture of cells on multi-organ-on-chip and parameter measurements in microfluidic devices. It underscores the advantage of microfluidic devices for developing efficient drug carrier particles, cell-free protein synthesis systems, and rapid techniques for direct drug screening. Further, it entails human-on-a-chip for measuring the systemic response as well as immediate effects of an organ reaction on other organs. In summary, this book reviews the development of a microfluidic-based organ-on-a-chip device for the preclinical evaluation, ADME studies of drugs, chemicals, and medical devices. This book is a valuable source for pharma companies, product developers, students, researchers, academicians, and practitioners.
Variant and related titles
Springer ENIN.
Other formats
Printed edition:
Printed edition:
Printed edition:
Format
Books / Online
Language
English
Added to Catalog
July 26, 2023
Contents
Chapter 1. A Historical and Technological Background to Organs-on-a-Chip
Chapter 2. Applications of microfluidics
Chapter 3. Microfluidics based Organ-on-a-chip for cell biology studies
Chapter 4. Microfluidics in Chemical biology
Chapter 5. Role of microfluidics in drug delivery
Chapter 6. Microfluidics in drug discovery
Chapter 7. Microfludic based sensors
Chapter 8. Background and Organs-on-a-Chip
Chapter 9. Culture and co-culture of cells for multi organ on chip
Chapter 10.Cells and organs on a chip in biomedical sciences
Chapter 11. Futuristic aspects of organ on a chip
Chapter 12. Development of Human on a chip
Chapter 13. Multi-organ on a chip for personalized medicine
Chapter 14. Development and application of Microfluids in organoid formation
Chapter 15. Liver on a chip
Chapter 16. Placenta on Chip: A Modern approach to probe feto-maternal interface
Chapter 17. Microfluidic retina-on-chip
Chapter 18. Heart on a chip
Chapter 19. Kidney on a chip
Chapter 20. Lungs on a chip
Chapter 21. Brain on a chip
Chapter 22. Skin on a chip
Chapter 23. Organs-on-a-chip in preclinical studies
Chapter 24. Application of organ on chip in blood brain barrier model
Chapter 25. Multi organs on a chip in disease modeling
Chapter 26. Prospects of Medical device on a chip
Chapter 27. Lab on a chip for precision Medicine
Chapter 28. Tumour-on-a-chip : Perfusion systems to model the extracellular breast tumour microenvironment:from tumour progression to metastasis formation
Chapter 29. Building Human In Vitro 3D Models to Replace Animal Studies: During Drug Discovery Reearch: Scientific, Ethical and Regulatory Considerations.
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