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Brody's human pharmacology : mechanism-based therapeutics
Title
Brody's human pharmacology : mechanism-based therapeutics / [edited by] Lynn Wecker ; with David A. Taylor, Robert James Theobald, Jr.
ISBN
9780323596626
0323596622
9780323596640
0323596649
9780323476522
032347652X
Edition
Sixth edition.
Publication
Philadelphia, PA : Elsevier, Inc., [2019]
Copyright Notice Date
©2019
Physical Description
1 online resource (xiv, 728 pages) : color illustrations
Local Notes
Access is available to the Yale community.
Access and use
Access restricted by licensing agreement.
Summary
"Focusing on the essential aspects of pharmacology you need to know, Brody's Human Pharmacology, 6th Edition, keeps you fully up to date with all that's new in the field. Streamlined content, a new organizational approach, enhanced online components, and thoroughly updated information ensure your grasp of key concepts and prepare you for exams. Nearly 500 full-color illustrations explain important processes, while color-coded boxes for major drugs, therapeutic overviews, clinical problems, and trade names reinforce your mastery of the information"--Publisher's description
Variant and related titles
Human pharmacology
Elsevier ClinicalKey eBooks. OCLC KB.
Other formats
Print version: Brody's human pharmacology. Sixth edition. Philadelphia : Elsevier, [2019]
Format
Books / Online
Language
English
Added to Catalog
August 02, 2023
Bibliography
Includes bibliographical references and index.
Contents
Section 1: Mechanisms of drug action and therapeutic principles.
Introduction, terminology
Pharmacodynamics: drug targets (receptors, enzymes, DNA, etc)
Pharmacokinetics
Pharmacogenomics
Drug discovery, development, and regulation
Section 2: Chemical mediators and drugs affecting autonomic and neuromuscular synapses.
Introduction to the peripheral nervous systems and drugs for peripheral disorders
Cholinergic drugs
Muscarinic agonists and their clinical uses
Muscarinic antagonists and their clinical uses
Nicotinic agonists and their clinical uses
Nicotinic antagonists and neuromuscular blocking drugs
Adrenergic drugs
Adrenergic agonists and their clinical uses
Adrenergic antagonists and their clinical uses
Section 3: Drug treatment for disorders affecting the central nervous system. Introduction to the CNS and drugs affecting the brain
Neurodegenerative disorders
Drug therapy for Alzheimer's disease and other cognitive disorders/dementias
Pharmacotherapy of basal ganglia disorders: Parkinson's disease and Huntington's disease
Drug therapy for psychoses and bipolar disorder
Drug therapy for depression and anxiety
Drug therapy for the management of attention deficit hyperactivity disorder
Drug therapy for insomnia and the hypersomnias
Drug therapy for managing obesity and eating disorders
Treatment of seizure disorders
Drug therapy to control spasticity disorders
Ethanol, other alcohols, and drugs for alcohol use disorder
Illicit psychoactive compounds and substance use disorder
Section 4: Drug therapy for pain management. Introduction
General anesthetics
Local anesthetics
Opioid analgesics
Nonsteroidal anti-inflammatory agents and acetaminophen
Cannabinoids
Section 5: Treatment of inflammatory, allergic and immunologic disorders. Drug therapy for migraine headache
Drug therapy for gout and hyperuricemia
Drug treatment for allergic reactions
Immunosuppressants for autoimmune disorders and organ transplantation
Drug therapy for rheumatoid arthritis
Section 6: Drug treatment for cardiovascular diseases. Introduction to the cardiovascular system and the regulation of blood pressure and heart rate
Overview of hypertension management and drugs that decrease sympathetic tone
Diuretics and drugs that affect volume and electrolyte content
Drugs affecting the renin-angiotensin-aldosterone system
Calcium channel blockers
Vasodilators
Drug therapy for hyperlipidemias and atherosclerotic cardiovascular disease
Drug therapy for myocardial ischemia and angina pectoris
Treatment of heart failure: cardiac glycosides, phosphodiesterase inhibitors and other agents
Antiarrhythmic drugs
Anticoagulant, antiplatelet and thrombolytic agents
Drug therapy for hemophilia and the anemias
Section 7: Treatment of endocrine disorders. Introduction to endocrine pharmacology
Treatment of hypothalamic and pituitary disorders
Treatment of adrenalcorticosteroid disorders
Female hormone regulation
Androgens, antiandrogens and their clinical uses
Drug therapy for the management of diabetes
Drug therapy for the management of thyroid disorders
Calcium regulating hormones and agents affecting bone
Section 8: Chemotherapy. Infectious diseases
Principles of antimicrobial use
Bacterial cell wall synthesis inhibitors
Inhibitors of protein synthesis
Drugs that target DNA
Antimycobacterial drugs and the treatment of tuberculosis and leprosy
Drug therapy for resistant organisms
Parasitic diseases
Antifungal agents
Antimalarial and other antiprotozoal agents
Antihelmintics
Viruses
Drug therapy for non-HIV viral infections
Drugs for HIV and related opportunistic infections
Cancer
Introduction and therapeutic principles
Cytotoxic agents
Targeted agents
Section 9: Special considerations. Therapeutic use of hematopoietic growth factors, vitamins and minerals
Gastrointestinal disorders and their treatment
Pharmacological treatment of asthma and COPD
The role of neutraceuticals and natural products
Essentials of toxicology
Therapeutic considerations for pregnant, pediatric, geriatric and obese individuals.
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