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Toll-Like Receptors Methods and Protocols
Title
Toll-Like Receptors [electronic resource] : Methods and Protocols / edited by Francesca Fallarino, Marco Gargaro, Giorgia Manni.
ISBN
9781071633663
Edition
1st ed. 2023.
Publication
New York, NY : Springer US : Imprint: Humana, 2023.
Physical Description
1 online resource (XI, 286 p.) 45 illus., 42 illus. in color.
Local Notes
Access is available to the Yale community.
Access and use
Access restricted by licensing agreement.
Summary
This volume provides methods on the role of TLRs in immune responses and on the various approaches targeting different TLRs in cancer, autoimmunity and in vaccine development. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Toll-Like Receptors: Methods and Protocols aims to be a useful and practical guide to new researchers and experts looking to expand their knowledge. .
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Springer protocols (Series)
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Format
Books / Online
Language
English
Added to Catalog
September 19, 2023
Series
Methods in Molecular Biology, 2700
Contents
Modelling of transmembrane domain and full length TLRs in membrane models
Development of Optimal Virtual Screening Strategies to Identify Novel Toll-like Receptor Ligands using the DockBox Suite
Use of Fluorescent Chemical Probes in the Study of Toll-like Receptors (TLRs) Trafficking
Use of Fluorescent Chemical Probes in the Study of Toll-like Receptors (TLRs) Trafficking
Endotoxin-tolerance mimicking to study TLR in promotion of tolerogenic DCs and Tr1 cells
Flow cytometry analysis of IL-1 receptors and Toll like receptors on platelets and platelet-derived extracellular vesicles
Methods to study TLRs in transplantation
Determining endosomal Toll-like Receptors gene expression in NK cells after stimulation with specific agonists
In vitro study of TLR4-NLRP3-inflammasome activation pathway in innate immune response
Toll-like receptor polymorphisms and the risk of cancer: meta-analysis study
Unrevealing the role of TLRs in the pathogenesis of autoimmune disease by using mouse model of diabetes
In vitro and ex vivo methodologies for T cell trafficking through Blood Brain Barrier after TLR activation
Delineating the role of Toll-like receptors in inflammatory bowel disease
Analysis of differential TLR activation in a mouse model of multiple sclerosis
Study of agonists of TLRs as vaccine adjuvants
Activation of TLRs by opportunistic fungi in lung organoids. .
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