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VIDEO 291-2B: Pharmacologic modulation of mutant CFTR. Describes CFTR encoding a maturational processing (protein biogenesis, class II) defect
Author
Title
VIDEO 291-2B: Pharmacologic modulation of mutant CFTR. Describes CFTR encoding a maturational processing (protein biogenesis, class II) defect. / Joseph Loscalzo, Eric J. Sorscher.
Publication
New York, N.Y. : McGraw-Hill Education LLC., 2022.
Physical Description
1 online resource (1 video file, approximately 22 sec.) : digital, .flv file, sound.
Local Notes
Access is available to the Yale community.
Notes
Title from title frames.
Later video (B) describes CFTR encoding a maturational processing (protein biogenesis, class II) defect. The mutant protein is misfolded, fails to traffic to the cell surface, and is degraded by the proteasome. Binding of corrector molecules (red spheres) improves folding and facilitates CFTR stabilization and cell surface localization/function. (Reproduced with permission from Cystic Fibrosis Foundation.)
Originally produced by Joseph Loscalzo. in 2022.
In English.
Description based on online resource; title from title screen (Internet Archive, viewed April 20, 2022)
Access and use
Access restricted by licensing agreement.
Variant and related titles
McGraw-Hill's AccessPharmacy.
Format
Images / Online / Video & Film
Language
English
Added to Catalog
September 21, 2023
Series
McGraw-Hill's AccessPharmacy
Videorecording number
19828655 McGraw-Hill Education LLC
Subjects
Genre/Form
Internet videos
Also listed under
McGraw-Hill Education LLC. publisher.
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