"Developed from a symposium sponsored by the Division of Carbohydrate Chemistry at the 207th National Meeting of the American Chemical Society, San Diego, California, March 13-18, 1994."

Distributed in print by Oxford University Press.

Description based on publisher-supplied information and home-page.

Original

Original

Online version

ACS symposium series, 580

Carbohydrates: Synthetic Methods and Applications in Antisense Therapeutics: An Overview / Sanghvi, Yogesh S.; Cook, P. Dan / http://dx.doi.org/10.1021/bk-1994-0580.ch001

Novel Backbone Replacements for Oligonucleotides / De Mesmaeker, Alain; Waldner, Adrian; Lebreton, Jacques; Fritsch, Valérie; Wolf, Romain M. / http://dx.doi.org/10.1021/bk-1994-0580.ch002

Synthesis of Nonionic Oligonucleotide Analogues / Maddry, Joseph A.; Reynolds, Robert C.; Montgomery, John A.; Secrist, John A. / http://dx.doi.org/10.1021/bk-1994-0580.ch003

Synthesis and Hybridization Properties of DNA Oligomers Containing Sulfide-Linked Dinucleosides / Just, George; Kawai, Stephen H. / http://dx.doi.org/10.1021/bk-1994-0580.ch004

4'-Thio-RNA: A Novel Class of Sugar-Modified β-RNA / Bellon, Laurent, Current address: Isis Pharmaceuticals, 2292 Faraday Avenue, Carlsbad, CA 92008; Leydier, Claudine; Barascut, Jean-Louis; Maury, Georges; Imbach, Jean-Louis / http://dx.doi.org/10.1021/bk-1994-0580.ch005

Hexopyranosyl-Like Oligonucleotides / Herdewijn, Piet, Laboratory of Medicinal Chemistry, Rega Institute, Minderbroedersstraat 10, B-3000 Leuven, Belgium; De Winter, Hans, Laboratory of Analytical Chemistry and Medicinal Fysicochemistry, Katholieke Universiteit Leuven, Van Evenstraat 4, B-3000 Leuven, Belgium; Doboszewski, Bogdan, Laboratory of Medicinal Chemistry, Rega Institute, Minderbroedersstraat 10, B-3000 Leuven, Belgium; Verheggen, Ilse, Laboratory of Medicinal Chemistry, Rega Institute, Minderbroedersstraat 10, B-3000 Leuven, Belgium; Augustyns, Koen, Laboratory of Medicinal Chemistry, Rega Institute, Minderbroedersstraat 10, B-3000 Leuven, Belgium; Hendrix, Chris, Laboratory of Medicinal Chemistry, Rega Institute, Minderbroedersstraat 10, B-3000 Leuven, Belgium; Saison-Behmoaras, Tula, Laboratoire de Biophysique, Muséum National D'Histoire Naturelle, rue Cuvier 43, F-75231 Paris, France; De Ranter, Camiel, Laboratory of Analytical Chemistry and Medicinal Fysicochemistry, Katholieke Universiteit Leuven, Van Evenstraat 4, B-3000 Leuven, Belgium; Van Aerschot, Arthur, Laboratory of Medicinal Chemistry, Rega Institute, Minderbroedersstraat 10, B-3000 Leuven, Belgium / http://dx.doi.org/10.1021/bk-1994-0580.ch006

/ Bolli, M., Institute of Organic Chemistry, University of Bern, CH-3012 Bern, Switzerland; Lubini, P., Laboratory of Organic Chemistry, Federal Institute of Technology, CH-8092 Zurich, Switzerland; Tarköy, M., Institute of Organic Chemistry, University of Bern, CH-3012 Bern, Switzerland; Leumann, C., Institute of Organic Chemistry, University of Bern, CH-3012 Bern, Switzerland / http://dx.doi.org/10.1021/bk-1994-0580.ch007

2',5'-Oligoadenylate Antisense Chimeras for Targeted Ablation of RNA / Torrence, Paul F., Section on Biomedical Chemistry, Laboratory of Medicinal Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892; Xiao, Wei, Section on Biomedical Chemistry, Laboratory of Medicinal Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892; Li, Guiying, Section on Biomedical Chemistry, Laboratory of Medicinal Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892; Lesiak, Krystyna, Section on Biomedical Chemistry, Laboratory of Medicinal Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, Current Address: Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Bethesda, MD 20872; Khamnei, Shahrzad, Section on Biomedical Chemistry, Laboratory of Medicinal Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892; Maran, Avudaiappan, Department of Cancer Biology, Cleveland Clinic Foundation, Cleveland, OH 44195; Maitra, Ratan, Department of Cancer Biology, Cleveland Clinic Foundation, Cleveland, OH 44195; Dong, Beihua, Department of Cancer Biology, Cleveland Clinic Foundation, Cleveland, OH 44195; Silverman, Robert H., Department of Cancer Biology, Cleveland Clinic Foundation, Cleveland, OH 44195 / http://dx.doi.org/10.1021/bk-1994-0580.ch008

Branched Nucleic Acids: Synthesis and Biological Applications / Hudson, R. H. E.; Ganeshan, K.; Damha, M. J., Corresponding author, current address: Department of Chemistry, McGill University, Montréal PQ H3A 2K6, Canada / http://dx.doi.org/10.1021/bk-1994-0580.ch009

Anti-Human Immunodeficiency Virus Activity and Mechanisms of Unmodified and Modified Antisense Oligonucleotides / Hatta, T.; Kim, S.-G.; Suzuki, S.; Takaki, K.; Takaku, H. / http://dx.doi.org/10.1021/bk-1994-0580.ch010

Carboranyl Oligonucleotides for Antisense Technology and Boron Neutron Capture Therapy of Cancers / Schinazi, Raymond F., Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, Atlanta Veterans Affairs Medical Center, Decatur, GA 30033; Lesnikowski, Zbigniew J., Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, Atlanta Veterans Affairs Medical Center, Decatur, GA 30033; Fulcrand-El Kattan, Géraldine, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, Atlanta Veterans Affairs Medical Center, Decatur, GA 30033; Wilson, David W., Department of Chemistry, Georgia State University, Atlanta, GA 30303 / http://dx.doi.org/10.1021/bk-1994-0580.ch011

Advances in Automated Chemical Synthesis of Oligoribonucleotides / Sinha, Nanda D.; Fry, Stephen / http://dx.doi.org/10.1021/bk-1994-0580.ch012

Anti-Human Immunodeficiency Virus Activity of a Novel Class of Thiopurine-Based Oligonucleotides / Meyer, Rich B.; Gall, Alexander A.; Gorn, Vladimir V. / http://dx.doi.org/10.1021/bk-1994-0580.ch013

New Twists on Nucleic Acids: Structural Properties of Modified Nucleosides Incorporated into Oligonucleotides / Griffey, Richard H.; Lesnik, Elena; Freier, Susan; Sanghvi, Yogesh S.; Teng, Kelly; Kawasaki, Andrew; Guinosso, Charles; Wheeler, Patrick; Mohan, Ventrankaman; Cook, P. Dan / http://dx.doi.org/10.1021/bk-1994-0580.c

Oligonucleotides > Derivatives.

Carbohydrate drugs > Synthesis.

Oligonucleotides > Technological innovations.

Oligonucleotides > Synthesis.

Oligomers > Synthesis.

Ablative materials > Technological innovations.

Nucleic acids > Synthesis.

AIDS vaccines > Mechanism of action.

Cancer > Chemotherapy.

HIV infections > Treatment.

Nucleic acids > Structure > Genetic engineering.

Oligonucleotides, Antisense - chemical synthesis.

Carbohydrates - genetics.

Carbohydrates - therapeutic use.

Sulfides - chemistry.

Nucleosides - chemical synthesis.

Adenine Nucleotides.

Oligoribonucleotides - chemical synthesis.

Chimera.

Ablation Techniques.

Nucleic Acids - chemical synthesis.

Antiviral Agents - chemical synthesis.

Boron Neutron Capture Therapy.

Anti-HIV Agents - chemical synthesis.

American Chemical Society. Division of Carbohydrate Chemistry, sponsoring body.

American Chemical Society. Meeting (207th : 1994 : San Diego, California)