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Genetic Studies in Model Organisms From Classical to Modern Genetics
Author
Title
Genetic Studies in Model Organisms [electronic resource] : From Classical to Modern Genetics / by Kwang-Wook Choi.
ISBN
9789819708307
Edition
1st ed. 2024.
Publication
Singapore : Springer Nature Singapore : Imprint: Springer, 2024.
Physical Description
1 online resource (XVII, 470 p.) 337 illus., 239 illus. in color.
Local Notes
Access is available to the Yale community.
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Access restricted by licensing agreement.
Summary
This book reviews key advances and new fundamentals in genetics. The increasing importance of genetic approaches in diverse areas of biology and medical sciences constantly requires in-depth information on genetic discoveries and research strategies for advanced graduate-level students as well as current researchers. This book focuses on genetic studies of various animal model systems and their major contributions to establishing modern genetics. Information covered in this book is mostly based on original research papers that extend from classical to modern genetics and applications. The contents are organized into four parts. Part I introduces fundamental concepts and experimental strategies in classical genetics. Part II discusses molecular genetics with transposons, transgenesis, clonal analysis, and gene editing technologies. Part III emphasizes epigenetic regulation of genome organization and gene expression. Part IV integrates earlier parts with landmark genetic studies on non-coding RNAs in dosage compensation, programmed cell death, growth control related to cancer, and behavioral neurobiology. .
Variant and related titles
Springer ENIN.
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Printed edition:
Printed edition:
Format
Books / Online
Language
English
Added to Catalog
May 08, 2024
Series
KAIST Research Series,
Contents
Part I. Mendel, Genetic Models, and Mutations
Chapter 1. Mendel's Principles of Inheritance and Chromosome Theory
Chapter 2. Genetic Model Organisms
Chapter 3. Recombination and Chromosomal Rearrangements
Chapter 4. Loss-of-Function Mutagenesis in Forward Genetics
Part II. Transposons, Transgenesis, Gene Editing, and Genetic Mosaics
Chapter 5. Non-Mendelian Genetics: Transposable elements (I)
Chapter 6. Transposable Elements II: Insertional Mutagenesis
Chapter 7. Gain-of-Function and Gene Silencing
Chapter 8. Genetic Interaction, Epistasis, Modifiers
Chapter 9. Targeted Mutagenesis
Chapter 10. Transgenesis in Clonal Analysis
Part III. Epigenetics, Genome Organization, and piRNA
Chapter 11. Epigenetic Control of Gene Expression
Chapter 12. Chromosomal Interaction in Chromatin Organization
Chapter 13. Piwi and piRNA in Germline and Epigenetic Regulation
Part IV. Applications of Genetic Analysis
Chapter 14. Genetic Control of Dosage Compensation
Chapter 15. Genetics of Programmed Cell Death
Chapter 16. Genetics of Growth Control
Chapter 17. Genetic Studies on Behavior.
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