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Gene discovery for disease models
Title
Gene discovery for disease models [electronic resource] / edited by Weikuan Gu.
ISBN
9780470499467 (cloth)
9780470933930 (e-book)
Published
Hoboken, N.J. : Wiley, c2011.
Physical Description
xiii, 537 p., [15] p. of plates : col. ill.
Local Notes
Access is available to the Yale community.
Notes
Electronic reproduction. Palo Alto, Calif. : ebrary, 2011. Available via World Wide Web. Access may be limited to ebrary affiliated libraries.
Access and use
Access restricted by licensing agreement.
Format
Books / Online
Language
English
Added to Catalog
May 21, 2012
Bibliography
Includes bibliographical references and index.
Contents
Introduction : gene discovery-from positional cloning to genomic cloning
High throughput gene expression analysis and the identification of expression QTLs
DNA methylation in the pathogenesis of autoimmunity
Ccell-based analysis with microfluidic chip
Missing dimension : protein turnover rate measurement in gene discovery
Bioinformatics tools for the prediction of gene function
Determination of genomic locations of targeted genetic loci
Mutation discovery using high throughput mutation screening technology
Candidate screening through gene expression profile
Candidate screening through high-density SNP array
Gene discovery through direct genome sequencing
Candidate screening through bioinformatics tools
Using an integrative strategy to identify mutations
Determination of the function of a mutant in a gene
Confirmation of a mutation by multiple molecular approaches
Confirmation of a mutation by microRNA
Confirmation of function of a gene by translational approaches
Confirmation of single nucleotide mutations
Initial identification and confirmation of a QTL gene
Gene discovery of crop diseases in the post genome era
Impact of whole genome genetic element analysis on gene discovery of disease models
Impact of whole genome protein analysis on gene discovery of disease models.
Also listed under
ebrary, Inc.
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