Books+ Search Results
Jaagsiekte Sheep Retrovirus and Lung Cancer
Author
Title
Jaagsiekte Sheep Retrovirus and Lung Cancer [electronic resource] / edited by Hung Fan.
ISBN
9783642556388
Published
Berlin, Heidelberg : Springer Berlin Heidelberg, 2003.
Physical Description
1 online resource.
Local Notes
Access is available to the Yale community.
Access and use
Access restricted by licensing agreement.
Summary
Retroviruses have been of great importance to biomedical science for the past half century. Initially, studies on oncogenic animal retroviruses provided important insights into molecular processes in carcinogenesis�– most notably the existence and mechanisms of action of oncogenes and proto-oncogenes. Moreover, several human diseases are caused by retroviruses, including AIDS, adult T-cell leukemia and the neurological disease HAM/TSP. The topic of this volume is a relatively unknown animal retrovirus, jaagsiekte sheep retrovirus, the causative agent of transmissible lung cancer in sheep –ovine pulmonary adenocarcinoma. The disease was first documented in South Africa in the 1800s, it has a wide geographical distribution, and it is of economic importance in high endemic regions. However, until very recently the nature of the etiologic agent was unclear, and relatively few laboratories actively studied the disease.
Variant and related titles
Springer ebooks.
Other formats
Printed edition:
Format
Books / Online
Language
English
Added to Catalog
February 05, 2013
Series
Current Topics in Microbiology and Immunology, 275
Contents
A history of ovine pulmonary adenocarcinoma (jaagsiekte) and experiments leading to the deduction of the JSRV nucleotide sequence
Pathology of ovine pulmonary adenocarcinoma
Natural history of JSRV in sheep
Molecular biology of jaagsiekte sheep retrovirus (JSRV)
Endogenous retroviruses related to jaagsiekte sheep retrovirus
Transformation and oncogenesis by jaagsiekte sheep retrovirus
Identification of Hyal2 as the cell-surface receptor for JSRV and ONAV
Enzootic nasal adenocarcinoma of sheep and goats
Pathology of human bronchiolo-alveolar carcinoma and its relationship to the ovine disease
Subject index.
Subjects
Also listed under
SpringerLink (Online service)
Bookmark As
Citation
