Books+ Search Results
Aging at the Molecular Level
Author
Title
Aging at the Molecular Level [electronic resource] / edited by Thomas Zglinicki.
ISBN
9789401706674
Published
Dordrecht : Springer Netherlands : Imprint: Springer, 2003.
Physical Description
X, 248 p. digital.
Local Notes
Access is available to the Yale community.
Access and use
Access restricted by licensing agreement.
Summary
During the last 40 years, the study of the biological basis of aging has progressed tremendously, and it has now become an independent and respectable field of study and research. The essential cause of aging is molecular damage that slowly overwhelms cellular and organismic defense, repair and maintenance systems. In recent years, a wealth of highly sophisticated research has transformed this idea from a credible hypothesis not only to a major theory, but essentially to accepted knowledge. Aging at the Molecular Level examines the key elements in this transformation. Bringing together contributions from an international team of authors, this volume will be of interest to graduates and postgraduates in the fields of medicine and nursing, researchers of different aspects of biogerontology and those in the pharmaceutical, cosmeceutical, nutraceutical and health-care industry.
Variant and related titles
Springer ebooks.
Other formats
Printed edition:
Format
Books / Online
Language
English
Added to Catalog
July 02, 2013
Series
Biology of Aging and Its Modulation ; 1
Contents
Editorial: About the series ‘Biology of aging and its modulation". Preface
1. Free radical production and antioxidant defense: a primer
2. Oxidative DNA damage and repair – implications for aging
3. Oxidative damage to proteins
4. Ageing rate, mitochondrial free radical production and constitutive sensitivity to lipid peroxidation: insights from comparative studies
5. Genomic instability in human premature aging
6. Oxidative damage, somatic mutations and cellular aging
7. Mitochondria and aging
8. Biological clocks in the aging cell
9. Telomeric damage in aging
10. Probing the in vivo relevance of oxidative stress in aging using knockout and transgenic mice
11. Non-oxidative modification of DNA and proteins
12. Transcriptional and translational dysregulation during aging
13. Metabolic regulation of gene silencing and life span
14. The proteasome in aging
15. Aging and lysosomal degradation of cellular constituents
Index.
Also listed under
SpringerLink (Online service)
Bookmark As
Citation
