Contents: Who 3-step analgesic ladder for cancer pain
Overview of WHO cancer pain programme
Cancer pain: a global problem
UK national cancer patient survey
Cancer pain is still endemic in the developed world
Pain characteristics
Pain in advanced cancer
2007 EPIC survey
What has been achieved?
The problem
The science of pain mechanisms and pain control
Cancer pain is complex
Cancer pain scenarios
Aetiology of cancer pain
Chronic pain is mediated by immune/inflammatory mechanisms
The WHO resource allocation model
Validation of WHO ladder
What has impeded progress?
What is an "adjuvant" in pain control?
Current molecular neurotransmission targets for pain control
The solution
Several mechanism-based ways of treating cancer pain
Pyramid of modern approaches to cancer pain
Do anti-cancer treatments reduce pain?
How do opioids reduce pain and are they all the same?