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Cell cycle control by the ubiquitin system in mammals
Author
Title
Cell cycle control by the ubiquitin system in mammals [electronic resource] / Michele Pagano.
Published
London : Henry Stewart Talks, 2009.
Physical Description
1 online resource (1 streaming video file (35 min.) : color, sound).
Local Notes
Access is available to the Yale community.
Notes
Animated audio-visual presentation with synchronized narration.
Title from title frames.
Access and use
Access restricted by licensing agreement.
Format
Images / Online / Video & Film
Language
English
Added to Catalog
April 30, 2015
Series
The cell division cycle : controlling when and where cells divide and differentiate,
System details note
Mode of access: World Wide Web.
System requirements: Browser compatibility: updated Mozilla Firefox, Google Chrome, Safari or Internet Explorer 8+. Browser settings: enable JavaScript, enable cookies from the Henry Stewart Talks site. Required Desktop Browser plugins & viewers: Updated Adobe Flash Player & Adobe Acrobat Reader. Mobile device & operating system versions: Android v2.1+, iPhone 4+ (iOS v5.x+), iPad 2+ (iOS v5.x+), BlackBerry OS v7.0+, Windows Phone v6.5.1+.
Contents
Contents: Ubiquitin-proteasome system
What regulates the cell division cycle?
Cyclin dependent kinases
Advantages of regulated proteolysis
The hierarchy of the ubiquitin pathway
E2s and E3s ensure substrate specificity
Regulation of the cell cycle by proteolysis
Two major ubiquitin ligases control cell cycle progression
SCF ubiquitin ligases
Mechanism of catalysis by the SCF
F-box proteins
Skp2
betaTrcp1 and betaTrcp2
DNA replication stress
Fbxw7
Anaphase promoting complex or cyclosome
Cell cycle, ubiquitin system and cancer.
Publisher's number
2368 Henry Stewart Talks
Subjects
Subjects (Medical)
Genes, cdc.
Ubiquitins.
Bookmark As
Citation
