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Crohn's Disease and Ulcerative Colitis From Epidemiology and Immunobiology to a Rational Diagnostic and Therapeutic Approach
Title
Crohn's Disease and Ulcerative Colitis [electronic resource] : From Epidemiology and Immunobiology to a Rational Diagnostic and Therapeutic Approach / edited by Daniel C. Baumgart.
ISBN
9783319337036
Edition
2nd ed. 2017.
Publication
Cham : Springer International Publishing : Imprint: Springer, 2017.
Physical Description
XX, 695 p. 204 illus., 144 illus. in color : online resource.
Local Notes
Access is available to the Yale community.
Access and use
Access restricted by licensing agreement.
Summary
This new edition is a unique combined resource for physicians and scientists addressing the needs of both groups. In addition to stimulating exchange and collaboration and shortening the path between discovery and application of new knowledge, the book helps clinicians understand new therapeutic concepts from their origins. The volume serves as a comprehensive guide to the current diagnostic modalities, including enhanced imaging techniques such as MRI and CT enterography, virtual colonoscopy, ultrasound, and endomicroscopy, as well as conventional and complex immunomodulatory principles. The latest edition also includes revised chapters from the previous edition, as well as new chapters reflecting current developments in the field. Written by experts in their field, Crohn’s Disease and Ulcerative Colitis: From Epidemiology and Immunobiology to a Rational Diagnostic and Therapeutic Approach, Second Edition is of great value to gastroenterologists, surgeons, internists, pediatricians and gynecologists trainees, as well as all those involved in Crohn’s disease, ulcerative colitis, and related autoimmune disorders. .
Variant and related titles
Springer ebooks.
Other formats
Printed edition:
Format
Books / Online
Language
English
Added to Catalog
April 03, 2017
Contents
Foreword
Preface
Environmental Factors in the Epidemiology of Inflammatory Bowel Disease
The Immune System in Health
Understanding the Epithelial Barrier in IBD
Intestinal Microbiology and Ecology in Crohn’s Disease and Ulcerative Colitis
The Immune System in Inflammatory Bowel Disease: Antimicrobial Peptides
Vascular Responses to Intestinal Inflammation
Immunobiology of Human Dendritic Cells in Inflammatory Bowel Disease
Immunobiology of T-cells in Inflammatory Bowel Disease
Immunology of B-cells in Inflammatory Bowel Disease
Immune Cells: Monocytes and Macrophages
Immune Functions of Epithelial Cells in Inflammatory Bowel Disease
Autophagy and Endoplasmic Reticulum Stress
Matrix Metalloproteinases
Paradigm of T-cell Differentiation in Irritable Bowel Disease
Pharmacological Intervention Studies Using Mouse Models of Chronic Intestinal Inflammation
Stem Cells and Organoids to Study Epithelial Cell Biology in Inflammatory Bowel Disease
Enhanced Endoscopy
Magnetic Resonance Enterography
Computed Tomography Enterography and Inflammatory Bowel Disease
Ultrasound in Inflammatory Bowel Disease
Laboratory Evaluation, Including Novel Diagnostic Markers
Pathology of Inflammatory Bowel Disease
Objective Assessment of Clinical Disease Activity
Objective Assessment of Endoscopic Disease Activity and Mucosal Healing
Evaluation of Quality of Life in Crohn’s Disease and Ulcerative Colitis: What Is Health-Related Quality of Life?
Evaluation of Health Economics in Inflammatory Bowel Disease
The Natural History of Inflammatory Bowel Disease
Conventional Medical Management of Crohn’s Disease: Sulfasalazine
Steroid Therapy for Crohn’s Disease
Thiopurines in Crohn’s Disease
Conventional Medical Management of Crohn’s Disease: Methotrexate
Adalimumab for the Treatment of Crohn’s Disease
Biologic Therapy of Crohn’s Disease: Certolizumab
Biologic Therapy of Crohn’s Disease: Infliximab
Briakinumab and Ustekinumab: Anti-p40 Antibodies for Inflammatory Bowel Disease Treatment
Biologic Therapy of Crohn’s Disease: Natalizumab, Vedolizumab and anti-MadCAM
Optimal Management of Fistulizing Crohn’s Disease
Sulfasalazine and 5-aminosalicylates for Ulcerative Colitis
Conventional Therapy of Ulcerative Colitis: Corticosteroids
Medical Management of Ulcerative Colitis: Conventional Therapy—Azathioprine
Calcineurin Inhibitors in Ulcerative Colitis
Biologic Therapy in Moderate-to-Severe Ulcerative Colitis: Infliximab
Biologic Therapy of Ulcerative Colitis: Adalimumab
Biologic Therapy of Ulcerative Colitis: Golimumab
Biologic Therapy of Ulcerative Colitis: Natalizumab, Vedolizumab, Etrolizumab (rHUMab beta 7), antiMadCAM
Probiotics, Prebiotics, and Antibiotics in Inflammatory Bowel Disease
Biosimilars in the Treatment of Inflammatory Bowel Disease
Step-up versus Top-down Approach in Crohn’s Disease
Leukocytapheresis Therapy of Inflammatory Bowel Diease
Surgical Management of Crohn’s Disease and Ulcerative Colitis
Extraintestinal Manifestations: Autoimmune Hepatitis
Primary Sclerosing Cholangitis
Autoimmune Pancreatitis and Other Organ Involvement
Cutaneous and Oral Manifestations of Inflammatory Bowel Disease
Arthritis, Arthropathy and Osteoporosis in Inflammatory Bowel Disease
Nutrition in Inflammatory Bowel Disease
Pregnancy and Fertility in Inflammatory Bowel Disease
Pediatric Aspects of Inflammatory Bowel Disease
Management and Prevention of Infectious Diseases in Inflammatory Bowel Disease Patients
Incidence of Cancer and Screening in Inflammatory Bowel Disease
Inflammatory Bowel Diseases: How to Identify High Risk Patients
Patient Perspective on Inflammatory Bowel Disease
Patient Resources in Inflammatory Bowel Disease.
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