1. Epidemiology of Neurofibromatosis Type 1
2. Genetics and Pathway in Neurofibromatosis Type 1
3. Molecular Diagnosis for NF1
4. Diagnosis in NF1, Old and New
5. Clinical Features of NF1 in the Skin
6. Ocular Manifestations in Neurofibromatosis Type 1
7. Skeletal Manifestations in NF1
8. NF1 in Other Organs
9. Genomics of Peripheral Nerve Sheath Tumors Associated to Neurofibromatosis Type 1
10. Mechanotransduction and Nf1 Loss
Partner in Crime: New Hints for Neurofibroma Genesis
11. Diagnosis and Management of Benign Nerve Sheath Tumors in NF1: Evolution from Plexiform to Atypical Neurofibroma and Novel Treatment Approaches
12. Diagnosis and Management of Malignant Tumors in NF1: Evolution from Atypical Neurofibromas to Malignant Peripheral Nerve Sheath Tumors and Treatment Options
13. Neurological Complications in NF
14. Learning Disabilities and Behavior in Neurofibromatosis Type 1 Patients
15. Mosaic NF1
16. Legius Syndrome, Other Café -au-lait Diseases and Differential Diagnosis of NF1
17. Cancer Risk and Spectrum in Individuals with RASopathies
18. Therapeutical Approaches for NF1
19. Medical Follow up in Neurofibromatosis Type 1
20. Brief Notes on Pregnancy, Prenatal Diagnosis and Preimplantation Procedures in NF1
21. Proposal of New Diagnostic Criteria.