Introduction: Natural philosophy and instrumentality
"What was worth knowing" in 1500
Humanism and ancient wisdom: how to learn things in the sixteenth century
The alchemist, the craftsman, and the scholar
Mathematics challenges philosophy: Galileo, Kepler, and the mathematical practitioners
Mechanism and corpuscles : Descartes builds a universe
Extra-curricular activities: new homes for natural knowledge
Experiment: how to learn things about nature in the seventeenth century
Cartesians and Newtonians
Conclusion: what was worth knowing by the eighteenth century?