Front Cover ; Advances in Immunology ; Copyright Page ; Contents ; Contributors ; Chapter 1: Antigen Presentation by CD1: Lipids, T Cells, and NKT Cells in Microbial Immunity ; 1. Introduction; 2. The CD1 Antigen Presentation Pathway: Chemistry, Structure, and Cell Biology; 3. Group I CD1: CD1a, b, and c Molecules and T Cells; 4. Group II CD1: CD1d-Restricted T Cells: Activation, Function, and Role in Antimicrobial Immunity; 5. Role of CD1d-Restricted NKT Cells in Specific Microbial Infections; 6. Conclusions; Acknowledgments; References.
Chapter 2: How the Immune System Achieves Self-Nonself Discrimination During Adaptive Immunity 1. Introduction; 2. Is Peripheral Immune Regulation Necessary for Self-Nonself Discrimination?; 3. Self-Nonself Discrimination Achieved During Thymic Negative Selection Determines How the Adaptive Immunity is Regulated ... ; 4. The Impact of the Conceptual Framework of the ""Avidity Model"" on the Development and Control of Pathogenic Autoimm ... ; Acknowledgments ; References; Chapter 3: Cellular and Molecular Mechanisms in Atopic Dermatitis ; 1. Introduction.
2. Physiology and Immunology of Normal Skin3. Clinical Aspects of AD; 4. Epidemiology; 5. Genetics; 6. Pathophysiology of AD; 7. Animal Models of AD; 8. Treatment of AD; 9. Conclusion; Acknowledgments; References; Chapter 4: Micromanagers of Immune Cell Fate and Function ; 1. Introduction; 2. miRNA Biogenesis; 3. miRNA Regulation of Gene Expression; 4. miRNA Target Genes; 5. miRNAs Regulate Hematopoietic Differentiation and Immune Function; 6. miRNA Regulation of Lymphocyte Development and Function; 7. miRNA Regulation of Inflammatory Responses; 8. Viruses Harness the miRNA Machinery.
9. Some Viral miRNAs Mimic Host miRNAs10. Host miRNAs also Regulate Viral Replication; 11. Prospects for Manipulating miRNA Function for Immunomodulatory Therapy; Acknowledgment; References; Chapter 5: Immune Pathways for Translating Viral Infection into Chronic Airway Disease1 ; 1. Introduction; 2. Background for the Model; 3. cDC T Cell Immune Axis; 4. NKT Cell-Macrophage Immune Axis; 5. Summary; Acknowledgments; References; Subject Index ; Contents of Recent Volumes ; Color Plates.