Intro
Title
Copyright
Contents
Chapter 1 Overview of Injectable Hydrogels for 3D Bioprinting and Tissue Regeneration
1.1 General Introduction
1.2 Introduction to Hydrogels and Their Syntheses
1.3 The Characterizations of Hydrogels
1.4 Natural and Nature-inspired Injectable Hydrogels
1.5 Self-assembling Hydrogels Based on Natural Building Blocks
1.6 In Situ Forming Hydrogels
1.7 Injectable Biopolymer Hydrogels for Regenerative Medicine
1.8 Hydrogels Processing Techniques and Vascular Tissue Engineering
1.9 Rheological Aspects of Hydrogel Processing
1.10 Interface (Cell, Gel, Surface) and Biocompatibility in Gel Processing
1.11 Bioprinting Hydrogels and Tissue Engineering
1.12 3D Bioprinting Hydrogel for Hard Tissue Regeneration
1.13 3D-bioprinting for Engineering Complex Tissues and Vascularization
1.14 Hydrogels-Blood Interactions
1.15 Immune Reactions to 3D Printable Hydrogels and Their Immunomodulation for Tissue Engineering
1.16 Application of Natural Hydrogels for Cell Therapy: Focus on Osteoarthritis
1.17 Clinical Application and Regulation of Bioprinting Biomaterials Focusing on Hydrogels
1.18 Current Status of Commercialization of FDA-approved Hydrogels and Their Intellectual Properties
1.19 Concluding Remarks and Future Perspectives
References
Section 1: Hydrogel Synthesis and Characterizations
Chapter 2 Introduction to Hydrogel Synthesis and Crosslinking Methods for Developing Bioinks for 3D Bioprinting
2.1 Introduction of Biomaterials
2.2 Hydrogel Biomaterials and Their Classification
2.3 Hydrogel Synthesis Methods
2.3.1 Chemical Crosslinking of Hydrogels
2.3.2 Physically Cross-linked Hydrogels
2.4 Applications of Hydrogels in 3D Bioprinting
2.4.1 Issues in 3D Bioprinting Applications
2.4.2 Chemical Crosslinking-based Hydrogels in 3D Printing
2.4.3 Physical Crosslinking-based Hydrogels in 3D Printing
2.5 Conclusion
Abbreviations
References
Chapter 3 Characterizations of Hydrogels
3.1 Introduction
3.2 Physical Properties of Hydrogels
3.2.1 Structure and Surface Topography
3.2.2 Porosity and Mesh Size
3.2.3 Swelling Ratio
3.2.4 Viscoelastic Properties
3.2.5 Mechanical Strength
3.2.6 Thermal Properties
3.2.7 Gelation Time
3.3 Chemical Properties
3.3.1 Chemical Compositions
3.3.2 Degradation
3.3.3 Wettability of Surface
3.4 Characterization of Tissue-engineering Hydrogel
3.4.1 Biocompatibility
3.4.2 Bioadhesiveness
3.4.3 Biodegradation
3.4.4 Biofunctionality
3.5 Conclusion
References
Chapter 4 Naturally Occurring and Nature-derived Polymers as Injectable Hydrogels
4.1 Introduction
4.2 Biopolymers for Injectable Hydrogels
4.2.1 Protein-based Hydrogels
4.2.2 Polysaccharide-based Hydrogels
4.3 Biosynthesis Strategies
4.4 Concluding Remarks
References
Chapter 5 Self-assembling Hydrogels Based on Natural Building Blocks