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Ageing and Dementia Current and Future Concepts
Title
Ageing and Dementia [electronic resource] : Current and Future Concepts / edited by Kurt Jellinger, Reinhold Schmidt, Manfred Windisch.
ISBN
9783709161395
Edition
1st ed. 2002.
Publication
Vienna : Springer Vienna : Imprint: Springer, 2002.
Physical Description
1 online resource (VIII, 384 p.)
Local Notes
Access is available to the Yale community.
Access and use
Access restricted by licensing agreement.
Summary
Epidemiological studies, modern clinical, neuroimaging, neuropsychological, molecular biological, and genetic studies have considerably enhanced our knowledge about ageing processes of the human brain, its sequelae, diagnostic, and therapeutic possibilities and limits. In addition to Alzheimer's disease and other degenerative dementias, the impact of cerebrovascular lesions and their risk factors in the pathogenesis of cognitive disorders of the aged are increasingly acknowledged, and the recognition of mild cognitive impairment as a frequent initial stage of developing dementia is becoming an increasingly important diagnostic and therapeutic problem. The included papers were presented at the 7th International Symposium in Graz, Sept. 2001 and give a timely overview of the current and future concepts of pathogenesis, diagnosis, and treatment strategies of pathological brain ageing and dementias, early recognition of mild cognitive impairment and future possiblities of prevention of dementing processes.
Variant and related titles
Springer ENIN.
Other formats
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Printed edition:
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Format
Books / Online
Language
English
Added to Catalog
July 05, 2022
Series
Journal of Neural Transmission. Supplementa ; 62
Contents
Vascular-ischemic dementia: an update
Frequency of white matter lesions and silent lacunar infarcts
CT and MRI rating of white matter changes
Risk factors and progression of small vessel disease-related cerebral abnormalities
Microangiopathy-related cerebral damage and angiotensinogen gene: from epidemiology to biology
Can small-vessel desease-related cerebral abnormalities be used as a surrogate marker for vascular dementia trials?
Reactive oxygen: its sources and significance in Alzheimer disease
Dysregulation of neuronal differentiation and cell cycle control in Alzheimer's disease
A broader horizon of Alzheimer pathogenesis: ALZAS - an early serum biomarker?
Is mild cognitive impairment bridging the gap between normal aging and Alzheimer's disease?
Vienna Transdanube Aging "VITA": study design, recruitment strategies and level of participation
Conversion from preclinical to clinical stage of Alzheimer's disease as shown by decline of cognitive function in carriers of the Swedish APP-mutation
The role of biological markers in the early and differential diagnosis of Alzheimer' disease
Measuring cognition in advanced Alzheimer's disease for clinical trials
Current drugs and future hopes in the treatment of Alzheimer'r disease
Development of human antibody fragments directed towards synaptic acetylcholinesterase using a semisynthetic phase display library
Long-term stabilizing effect of cholinesterase inhibitors in the therapy of Alzheimer' disease
Impact of muscarinic agonists for successful therapy of Alzheimer's disease
Nicotinic receptor modulation: advantages for successful Alzheimer's disease therapy
Glutamate receptors as a target for Alzheimer's disease - are clinical results supporting the hope?
Can estrogen play a significant role in the prevention of Alzheimer's disease?
Neurotrophic factors and Alzheimer's disease: are we focusing on the wrong molecule?
Nerve growth factor and cholinergic CNS neurons studied in organotypic brain slices
Sustained improvement of cognition and global function in patients with moderately severe Alzheimer's disease: a double-blind, placebo-controlled study with the neurotrophic agent Cerebrolysin®
Improved global function and activities of daily living in patients with AD:.a placebo-controlled clinical study with the neurotrophic agent Cerebrolysin®
Genomics and dementia - new drug targets ahead?
Are ?-sheet breaker pertides dissolving the therapeutic problem of Alzheimer's disease?
Glycoxidative stress creates a vicious cycle of neurodegeneration in Alzheimer's disease - a target for neuroprotective treatment strategies?
Pharmacological targets to inhibit Alzheimer neurofibrillary degeneration
Generation and brain delivery of anti-aggregating anti-bodies against ?-amyloid plaques using phage display technology
Effects of Cerebrolysin™ on amyloid-? deposition in a transgenic model of Alzheimer's disease
Vitamin E binding protein Afamin protects neuronal cells in vitro
Recent developments in the pathology of Parkinson's disease.
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