Cover
Title Page
Copyright Page
Contents
Preface
Acknowledgments
CHAPTER 1 Introduction
1.1 Nanomaterials
1.2 Microfluidics
1.3 DNA and RNA Technology
1.4 Lab-on-a-Chip Devices
1.5 Outline of the Book
1.6 References
CHAPTER 2 Microfluidics I: Forces, Thermodynamics, and Fluid Flow
2.1 Introduction
2.2 Forces
2.3 Thermodynamics
2.4 Mechanical Forces
2.5 Pressure-Driven Flow (PDF)
2.6 Electro-Osmotic Flow (EOF)
2.7 Problems
2.8 References
CHAPTER 3 Microfluidics II: Fluid Transport and Applications
3.1 Diffusion
3.2 Electrophoretic Flow (EPF)
3.3 Dielectrophoretic (DEP) Force
3.4 Comparison of Fluid Transport Methods
3.5 Applications
3.6 Problems
3.7 References
CHAPTER 4 Optical Detection and Quantum Dots
4.1 Introduction to Optics
4.2 Optical Detection and Fluorescence
4.3 Quantum Dots
4.4 Problems
4.5 References
CHAPTER 5 DNA and RNA Bionanotechnology
5.1 Introduction to DNA and RNA
5.2 Polymerase Chain Reaction (PCR)
5.3 Detection of DNA Mutations
5.4 DNA Sequencing
5.5 RNA Sequencing and Synthesis
5.6 DNA Self-Assembly
5.7 DNA Tweezers
5.8 CRISPR Gene Editing
5.9 Problems
5.10 References
CHAPTER 6 Lab-on-a-Chip Bionanotechnology and Micro/Nano Fabrication
6.1 Overview of Lab-on-a-Chip Devices
6.2 Lab-on-a-Chip Biosensors
6.3 Organ-on-a-Chip Devices
6.4 Micro/Nano Fabrication Techniques
6.5 Micro/Nano Fabrication of Microfluidic and Lab-on-a-Chip Devices
6.6 References
CHAPTER 7 Applications of Bionanotechnology
7.1 Equivalent Circuit Models for Mechanical, Fluidic, and Thermal Systems
7.2 Polymerase Chain Reaction Microreactors
7.3 Diabetic Glucose Monitoring with Bionanotechnology
7.4 Bacteriophage Therapy
7.5 Biomedical Applications of Nanoparticles
7.6 Targeted Cancer Therapies and Drug Delivery Systems
7.7 Mitochondria-Targeted Delivery of 2,4-Dinitrophenol by Nanoparticles
7.8 Neural Implants and Brain?Machine Interfaces
7.9 Applications of Bionanotechnology in Crop Agriculture
7.10 References
CHAPTER 8 Computer Simulations with COMSOL Multiphysics? Software
8.1 Lab#1: 2D Simulation of Interdigitated Electrodes
8.2 Lab #2: 3D Simulation of Interdigitated Electrodes
8.3 Lab #3: Tracing Dielectrophoretic Particle Motion
APPENDIX A Abbreviations
APPENDIX B Units in SI (International System of Units)
APPENDIX C Fundamental Physical Constants
APPENDIX D Sign Convention for Fluid Flow
APPENDIX E Coordinate Systems
APPENDIX F Complex Numbers
Index.