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Innate immunity, inflammation and cancer from bench to bedside
Title
Innate immunity, inflammation and cancer [electronic resource] : from bench to bedside / Alberto Mantovani.
Published
London : Henry Stewart Talks, 2024.
Physical Description
1 online resource (1 streaming video file (69 min.) : color, sound).
Local Notes
Access is available to the Yale community.
Notes
Title from title frames.
Webinar.
Access and use
Access restricted by licensing agreement.
Summary
The innate immune system includes a cellular and a humoral arm. Tumor-associated macrophages (TAM) have served as a paradigm for the importance of the tumor microenvironment in tumor progression. Single cell analysis and spatial transcriptomics have provided new vistas on the complexity and function of TAM. Moreover, myeloid cells are a source of fluid phase pattern recognition molecules (ante-antibodies) and, in turn, humoral innate immunity shapes recruitment and function of these cells. TAM engage in complex bidirectional interactions with innate and adaptive lymphoid cells and stroma. Moreover, they play an important role in response and resistance to current immunotherapy approaches. Prof. Mantovani discusses how myeloid cells represent tools and targets for innovative therapeutic approaches, complementing current strategies..
Format
Images / Online / Video & Film
Language
English
Added to Catalog
May 08, 2024
Series
The biomedical & life sciences collection,
Publisher's number
11014 Henry Stewart Talks
Subjects
Subjects (Medical)
Gene Expression Profiling.
Immunity, Innate.
Myeloid Cells.
Single-Cell Analysis.
Tumor Microenvironment.
Tumor-Associated Macrophages.
Bookmark As
Citation
