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Cancer Cell Dormancy Methods and Protocols
Title
Cancer Cell Dormancy [electronic resource] : Methods and Protocols / edited by Marco Montagner.
ISBN
9781071638828
Edition
1st ed. 2024.
Publication
New York, NY : Springer US : Imprint: Humana, 2024.
Physical Description
1 online resource (XII, 222 p.) 67 illus., 61 illus. in color.
Local Notes
Access is available to the Yale community.
Access and use
Access restricted by licensing agreement.
Summary
This volume provides protocols and techniques to study metastatic dormant cells. Chapters focus on in vitro systems to model metastatic dormancy in vitro, detection of disseminated tumor cells in vivo, perturbation of key molecules involved in metastatic dormancy, and clinical features of delayed metastatic relapses of specific tumor types. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Cancer Cell Dormancy: Methods and Protocols aims to ensure successful results in the further study of this vital field.
Variant and related titles
Springer protocols (Series)
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Format
Books / Online
Language
English
Added to Catalog
August 07, 2024
Series
Methods in Molecular Biology, 2811
Contents
Clinical Tumor Dormancy
In vitro and in vivo systems to study tumor dormancy and the transition to overt metastases induced by the fibrotic milieu
Modeling tumor cell dormancy in an ex vivo liver metastatic niche
Bone marrow stoma co-cultivation model of breast cancer dormancy
Establishing and characterizing chemotherapy-induced immunological dormant tumor cell lines
In ovo xenograft model to study tumor dormancy, tumor cell dissemination and metastasis
Pre-clinical mouse intraductal model (MIND) to study metastatic dormancy in estrogen receptor-positive breast cancer
Intracardiac injection mouse model to study cancer cell dormancy in brain metastasis
Modeling the depth of cellular dormancy from RNA-sequencing data
Crispr knock-ins in organoids to track tumor cell subpopulations
A live tracker of dormant disseminated tumor cells
Characterizing rare dormant and cycling lineages using thewatermelon system
Kiss1 and kisspeptins detection in cell lines
Detection of ROS in dormant breast cancer cell.-13C tracer analysis and metabolomics in dormant cancer cells
Visualizing the cell-matrix interactions and cytoskeleton of disseminated tumor cells.
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