Contents: The TGFb family as a paradigm of multifunctional cytokines
TGFb controlling embryo development and tissue homeostasis
TGFb receptor serine/threonine kinases
SMADs as central TGFb signal transducers and transcriptional mediators
Logic and organization of TGFb signaling processes
TGFb pathway regulation and integration in the cell
TGFb pathway disruption in heritable disorders and cancer.