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Modulating gene expression to treat diseases

Title
Modulating gene expression to treat diseases [electronic resource] / Navneet Matharu.
Published
London : Henry Stewart Talks, 2021.
Physical Description
1 online resource (1 streaming video file (20 min.) : color, sound).
Local Notes
Access is available to the Yale community.
Notes
Animated audio-visual presentation with synchronized narration.
Title from title frames.
Access and use
Access restricted by licensing agreement.
Variant and related titles
Henry Stewart talks.
Format
Images / Online / Video & Film
Language
English
Added to Catalog
September 17, 2024
Series
Henry Stewart talks. Biomedical & life sciences collection.
The biomedical & life sciences collection,
Contents
Contents: Programmable DNA targeting modules
Effector domain functions and possibilities
Haploinsufficiency and its role in disease
CRISPRa targeting strategy to rescue Sim1 obesity
CRISPRa targeting strategy to treat Mc4r haploinsufficiency.
Publisher's number
5594 Henry Stewart Talks
Subjects (Medical)
Basic Helix-Loop-Helix Transcription Factors.
Clustered Regularly Interspaced Short Palindromic Repeats.
CRISPR-Cas Systems.
Gene Expression Regulation.
Gene Targeting - methods.
Genetic Diseases, Inborn - therapy.
Haploinsufficiency.
Loss of Function Mutation.
Obesity - genetics.
Obesity - therapy.
Receptor, Melanocortin, Type 4.
Repressor Proteins.
Up-Regulation.
Citation

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