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Vascular biology of the placenta
Author
Title
Vascular biology of the placenta [electronic resource] / Yuping Wang, Shuang Zhao.
ISBN
9781615040469 (electronic bk.)
9781615040452 (pbk.)
Published
San Rafael, Calif. (1537 Fourth Street, San Rafael, CA 94901 USA) : Morgan & Claypool, c2010.
Physical Description
1 electronic text (viii, 90 p. : ill.) : digital file.
Local Notes
Access is available to the Yale community.
Notes
Title from PDF t.p. (viewed on March 17, 2010).
Part of: Colloquium digital library of life sciences.
Summary
The placenta is an organ that connects the developing fetus to the uterine wall, thereby allowing nutrient uptake, waste elimination, and gas exchange via the mother's blood supply. Proper vascular development in the placenta is fundamental to ensuring a healthy fetus and successful pregnancy. This book provides an up-to-date summary and synthesis of knowledge regarding placental vascular biology and discusses the relevance of this vascular bed to the functions of the human placenta.
Format
Books / Online
Language
English
Added to Catalog
June 15, 2011
Series
Integrated systems physiology, from molecules to function to disease, # 9
Bibliography
Includes bibliographical references (p. 73-90).
Contents
1. Introduction
2. Placental blood circulation
2.1. Maternal-placental blood circulation
2.2. Fetal-placental circulation
3. Structure of the placenta
4. Cell types of the placenta
4.1. Cytotrophoblasts and syncytiotrophoblasts
4.2. Villous core stroma cells
4.3. Pericytes/endothelial cells
5. Oxygen tension and placental vascular development
5.1. Oxygen tension and establishment of maternal-placental circulation
5.2. Hypoxia and trophoblast differentiation
5.3. Models of placental hypoxia
6. Vasculogenesis and angiogenesis of human placenta
7. Angiogenic factors
7.1. VEGF family molecules and VEGF receptors
7.2. FGFs and FGF receptors
7.3. Angiopoietins and tie system
8. Vasoactivators and placental vasoactivity
8.1. Renin-angiotensin system
8.2. Arachidonic acid metabolites: thromboxane and prostacyclin
8.3. Endothelin-1 and its receptors
8.4. Nitric oxide
8.5. Chymase
8.6. Role of trophoblasts in regulation of placental vasoactivity
9. Lymphatic phenotypic characteristics of the human placenta
10. Placental tissue and cord blood stem cells
11. Summary
Acknowledgment
References.
Subjects
Subjects (Medical)
Placenta - blood supply.
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